Figure 3
Neutrophil priming ability. Ability to prime fMLP-induced human neutrophil respiratory burst function is shown as mean of n = 4 experiments. Error bars indicate SEM. Both "stored PRBC" and "stored PLT" display increased ability to prime fMLP-induced neutrophil respiratory burst than the equivalent fresh product. There was no difference between the ability of "stored PRBC" and "stored PLT" to prime fMLP-induced neutrophil respiratory burst. # P < 0.001 "stored PLT" vs. "fresh PLT" using a one-way ANOVA with Bonferroni's multiple comparisons adjustment. * P < 0.001 "stored PRBC" vs. "fresh PRBC" using a one-way ANOVA with Bonferroni's multiple comparisons adjustment. ns P > 0.05 "stored PRBC" vs. "stored PLT" using a one-way ANOVA with Bonferroni's multiple comparisons adjustment. ANOVA, analysis of variance; fMLP, N-formylmethionyl-leucyl-phenylalanine; "fresh PLT", pooled heat-inactivated supernatant from Day 1 non-leucoreduced human platelet concentrates; "fresh PRBC", pooled heat-inactivated supernatant from Day 1 non-leucoreduced human packed red blood cell concentrates; min, minute; O2-, superoxide anion; PAF, platelet activating factor; PLT, platelet concentrate, PRBC packed red blood cells; "stored PLT", pooled heat-inactivated supernatant from Day 5 non-leucoreduced human platelet concentrates; "stored PRBC", pooled heat-inactivated supernatant from day 42 non-leucoreduced human packed red blood cell concentrates; SEM, standard error of the mean.