Table 4 Renal perfusion and function
6% HES 130 | 10% HES 200 | RAc | 4% gelatin | SHAM | ||
|---|---|---|---|---|---|---|
Left renal artery flow, ml/kgBW/min | Baseline | 7.0 ± 2.9 | 7.5 ± 2.9 | 6.1 ± 2.2 | 6.8 ± 0.4 | 8.3 ± 3.7 |
Before sepsis | 5.3 ± 3.8 | 6.8 ± 2.6 | 4.6 ± 1.5 | 6.4 ± 0.5 | 8.9 ± 5.0 | |
12 h after sepsis | 9.6 ± 3.7 | 4.0 ± 3.1 | 5.0 ± 1.9 | 6.7 ± 2.0 | 11.4 ± 8.3 | |
Crea as percentage of baseline, % | Baseline | - | - | - | - | - |
Before sepsis | 4 ± 5 | 12 ± 5 ‡ | 10 ± 6 | 14 ± 6 ‡ | -2 ± 2 | |
12 h after sepsis | -13 ± 7 | 87 ± 84**; + | -4 ± 13 | 26 ± 13 | -4 ± 13 | |
Crea clearance, ml/min | Baseline | 136 ± 24 | 130 ± 87 | 108 ± 94 | 101 ± 46 | 117 ± 13 |
Before sepsis | 98 ± 47 | 57 ± 36 | 57 ± 51 | 48 ± 17 | 78 ± 10 | |
12 h after sepsis | 97 ± 15 | 13 ± 14 * | 76 ± 23 | 38 ± 8 ‡; + | 98 ± 48 | |
Urine output, ml/kgBW/h | Baseline | - | - | - | - | - |
Before sepsis | - | - | - | - | - | |
12 h after sepsis | 3.3 ± 1.3 | 0.5 ± 0.3 | 11.5 ± 12.3 | 1.1 ± 0.2 | 2.2 ± 1.9 | |
Cl, mmol/l | Baseline | 100 ± 1 | 100 ± 2 | 99 ± 2 | 100 ± 2 | 100 ± 1 |
Before sepsis | 100 ± 1 | 103 ± 2 | 100 ± 1 | 98 ± 2 | 101 ± 2 | |
12 h after sepsis | 103 ± 2 | 111 ± 2 | 109 ± 9 | 98 ± 2 **; ║ | 101 ± 2 | |
Na, mmol/l | Baseline | 135 ± 1 | 135 ± 2 | 136 ± 2 | 136 ± 1 | 136 ± 1 |
Before sepsis | 136 ± 2 | 138 ± 2 | 137 ± 3 | 138 ± 2 | 137 ± 1 | |
12 h after sepsis | 136 ± 2 | 140 ± 3 | 144 ± 11 | 138 ± 3 | 136 ± 2 | |
K + , mmol/l | Baseline | 4.5 ± 0.4 | 4.4 ± 0.3 | 4.5 ± 0.2 | 4.4 ± 0.1 | 4.4 ± 0.2 |
Before sepsis | 3.7 ± 0.2 | 3.8 ± 0.3 | 4.0 ± 0.2 | 3.9 ± 0.2 | 4.4 ± 0.1 | |
12 h after sepsis | 3.9 ± 0.5 | 5.6 ± 1.7 | 4.0 ± 0.3 | 4.9 ± 1.1 | 3.8 ± 0.1 | |
Aniongap mmol/l | Baseline | 10.2 ± 0.8 | 10.0 ± 0.3 | 9.9 ± 1.9 | 10.4 ± 0.5 | 10.4 ± 1.4 |
Before sepsis | 9.6 ± 0.3 | 9.2 ± 1.4 | 9.8 ± 1.3 | 11.4 ± 1.0 | 9.4 ± 1.4 | |
12 h after sepsis | 6.8 ± 0.7 | 10.9 ± 4.2 | 8.2 ± 1.2 | 15.4 ± 4.2**;+ | 9.5 ± 0.2 |