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Figure 2 | Critical Care

Figure 2

From: Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial

Figure 2

Progression of renal parameters. ( A ) Endogenous creatinine clearance is expressed as mean ± SEM (one-side depicted) and analyzed by ANOVA with repeated measurements over the complete curve (P = 0.01). Missing values were imputed from last-observation-carried forward (LOCF) from Day 7 to Day 28. ( B) Renal replacement therapy (RRT) requirement is expressed as percentage in total treatment group; analyzed by Fisher's exact test (P = 0.29). ( C ) RRT duration: hours per total number of patients in group (cumulative for multiple interventions) over study period, expressed as mean ± SEM; analyzed by independent t-test (P = 0.08). *: Primary variable analyzed by the Hartung method [22].

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