Relationship between thyroid function and ICU mortality: a prospective observation study

Table 4 Independent predictors of ICU mortality by multivariate logistic regression analysis in all patients (appending models summary)^a

Predictor	Standard β value	OR	P value	-2 log-likelihood	Cox & Snell R²	Nagelkerke R²
Model I APACHE II score	1.355	3.877	0.000	315.784	0.186	0.301
Model II
FT3	-0.741	0.477	0.000	295.291	0.225	0.364
APACHE II score	1.119	3.062	0.000
Final model
FT3	-0.600	0.549	0.001
APACHE II score	0.912	2.490	0.000
Log(NT-proBNP)	0.459	1.582	0.017	282.968	0.248	0.401
Log(CRP)	0.367	1.443	0.030

^aAPACHE II score, Acute Physiology and Chronic Health Evaluation II score; eGFR, estimated glomerular filtration rate; FT3, free triiodothyronine; FT4, free thyroxine; NT-proBNP, N-terminal pro-brain natriuretic peptide; rT3 = reverse triiodothyronine; T3 = triiodothyronine; T4 = thyroxine; TSH = thyroid-stimulating hormone; TT3 = total triiodothyronine; TT4 = total thyroxine; T3/rT3 = ratio of rT3 to T3. Standard β value was calculated using the semistandardization method (X standardization). Odds ratios are shown as standardized OR per 1 SD. Log variable is the logarithm of the variable. Independent variables in the multivariate analysis included TT3, TT4, FT3, FT4, rT3, TSH, T3/rT3, Log(NT-proBNP), Log(CRP), APACHE II score and albumin (and age, eGFR and hemoglobin). Variables not listed in the table were removed from the stepwise analysis.

ISSN: 1364-8535