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Table 1 Baseline clinical and laboratory characteristics of study subjectsa

From: Relationship between thyroid function and ICU mortality: a prospective observation study

Characteristics All Survivors Nonsurvivors P values
Number 480 388 92  
Males (%) 59.79 60.87 59.54 0.815
Age (years) 71.71 ± 15.52 70.62 ± 15.82 76.32 ± 13.28 0.0001
Principal diagnosis leading to ICU admission (%)     
   Pulmonary disease 32.50 33.51 28.26 0.334
   Cardiovascular disease 36.67 37.89 31.52 0.255
   Neurologic disease 7.50 6.96 9.78 0.355
   Digestive disease 5.0 5.41 3.26 0.395
   Renal insufficiency 1.88 1.55 3.26 0.276
   Poisoning 3.75 4.38 1.09 0.135
   Infectious disease and/or sepsis 4.38 2.58 11.96 < 0.0001
   Trauma 2.08 2.58 0.00 0.120
   Other 6.25 5.15 10.87 0.042
Accompanying infection (%) 44.38 41.75 55.43 0.018
Hemoglobin (g/L) 117.35 ± 23.77 119.51 ± 22.81 108.25 ± 25.67 < 0.0001
eGFR (mL/minute/1.73 m2) 66.13 (4.18 to 314.43) 71.63 (4.18 to 314.43) 39.95(4.25 to 238.71) < 0.0001
APACHE II score (points) 12.93 ± 6.67 11.38 ± 5.60 19.49 ± 6.85 < 0.0001
NT-proBNP (ng/ml) 2843.50 (20.95 to 35,000.00) 2201.00 (20.95 to 35,000.00) 8700.00 (142.40 to 35,000.0) < 0.0001
CRP (mg/L) 33.50 (1.00 to 160.00) 23.00 (1.00 to 160.00) 96.50 (6.00 to 160.00) < 0.0001
Albumin (g/L) 33.67 ± 4.98 34.41 ± 4.64 30.56 ± 5.18 < 0.0001
Thyroid function     
   TT3 (nmol/L) 1.11 ± 0.33 1.16 ± 0.32 0.89 ± 0.30 < 0.0001
   TT4 (nmol/L) 71.16 ± 21.81 73.92 ± 20.88 59.52 ± 21.92 < 0.0001
   FT3 (pmol/L) 3.42 ± 0.63 3.53 ± 0.60 2.95 ± 0.57 < 0.0001
   FT4 (pmol/L) 15.54 ± 3.40 15.80 ± 3.29 14.48 ± 3.66 0.0008
   rT3 (nmol/L) 0.30 (0.01 to 4.44) 0.30 (0.01 to 1.51) 0.30 (0.02 to 4.44) 0.4010
   TSH (IU/mL) 0.80 (0.04 to 23.07) 0.87 (0.04 to 23.87) 0.60 (0.05 to 12.73) 0.0022
   T3/rT3 3.36 (0.61 to 138.00) 3.62 (0.33 to 138.00) 2.61 (0.06 to 26.00) 0.0009
  1. aAPACHE II score, Acute Physiology and Chronic Health Evaluation II score; eGFR, estimated glomerular filtration rate; CRP, C-reactive protein; FT3, free triiodothyronine; FT4, free thyroxine; NT-proBNP, N-terminal pro-brain natriuretic peptide; rT3, reverse triiodothyronine; TSH, thyroid-stimulating-hormone; TT3, total triiodothyronine; TT4, total thyroxine; T3/rT3, the ratio of rT3 to T3.