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Table 3 Comparison of COXa/CSa and COXq/CSa ratios between JT and other mitochondrial DNA haplogroups

From: Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup

 

Other haplogroups

JT haplogroup

P value

Time of diagnosis

(n = 81)

(n = 15)

 

   COXa/CSa ratio

2.84 (2.37 to 3.16)

3.25 (2.63 to 3.56)

0.04

   COXq/CSa ratio

1.80 (1.25 to 2.90)

2.72 (1.57 to 3.38)

0.01

Day 4

(n = 62)

(n = 10)

 

   COXa/CSa ratio

2.81 (2.43 to 3.19)

3.24 (3.04 to 3.33)

0.01

   COXq/CSa ratio

1.67 (1.27 to 3.14)

3.10 (2.52 to 3.45)

0.004*

Day 8

(n = 55)

(n = 10)

 

   COXa/CSa ratio

2.72 (2.32 to 3.26)

3.07 (2.83 to 3.15)

0.04

   COXq/CSa ratio

1.67 (1.22 to 3.06)

3.39 (2.61 to 3.52)

0.002*

  1. Data presented as median (interquartile range). COXa/CSa, cytochrome c oxidase specific activity/citrate synthase specific activity; COXq/CSa, cytochrome c oxidase quantity/citrate synthase specific activity. *Statistically significant after Bonferroni correction.