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Table 3 Comparison of COXa/CSa and COXq/CSa ratios between JT and other mitochondrial DNA haplogroups

From: Survival and mitochondrial function in septic patients according to mitochondrial DNA haplogroup

  Other haplogroups JT haplogroup P value
Time of diagnosis (n = 81) (n = 15)  
   COXa/CSa ratio 2.84 (2.37 to 3.16) 3.25 (2.63 to 3.56) 0.04
   COXq/CSa ratio 1.80 (1.25 to 2.90) 2.72 (1.57 to 3.38) 0.01
Day 4 (n = 62) (n = 10)  
   COXa/CSa ratio 2.81 (2.43 to 3.19) 3.24 (3.04 to 3.33) 0.01
   COXq/CSa ratio 1.67 (1.27 to 3.14) 3.10 (2.52 to 3.45) 0.004*
Day 8 (n = 55) (n = 10)  
   COXa/CSa ratio 2.72 (2.32 to 3.26) 3.07 (2.83 to 3.15) 0.04
   COXq/CSa ratio 1.67 (1.22 to 3.06) 3.39 (2.61 to 3.52) 0.002*
  1. Data presented as median (interquartile range). COXa/CSa, cytochrome c oxidase specific activity/citrate synthase specific activity; COXq/CSa, cytochrome c oxidase quantity/citrate synthase specific activity. *Statistically significant after Bonferroni correction.