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Figure 2 | Critical Care

Figure 2

From: Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose

Figure 2

Effect of treatment with saline or ethyl pyruvate (EP) on pathology in acetaminophen-challenged mice. Hematoxylin-eosin staining was assessed 24 and 48 hours after induction of acute liver injury (or sham procedure). Method and treatment were the same as described in Figure 1 (n = 6 for each group). Since the three saline-treated groups (saline 2- to 48-hour group, saline 2- to 24-hour group, and saline 24- to 48-hour group) showed comparable pathology, only saline 2- to 48-hour treatment at 48 hours is shown. A typical picture is shown. (A = 24 h Saline, B = 48 h Saline, C = 2-24 h EP, D = 24 h EP, E = 48 h EP, F = 24-48 h EP).

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Critical Care

ISSN: 1364-8535