| |
Baseline
|
INO
|
Dobutamine
|
INO+Dobutamine
|
|---|
|
Cardiac index (l/min/m2)
|
3.2 ± 1.9
|
3.2 ± 2.3
|
5.0 ± 2.7
|
4.7 ± 2.4**
|
|
Heart rate (beats/min)
|
83 ± 28
|
83 ± 30
|
104 ± 28
|
101 ± 29*
|
|
SVI (ml/m2)
|
38 ± 11
|
39 ± 13
|
49 ± 18
|
47 ± 19
|
|
CVP (mmHg)
|
2.5 ± 3
|
2.5 ± 3.1
|
2.0 ± 1.8
|
2.0 ± 2.0
|
|
MPAP (mmHg)
|
23 ± 7
|
21 ± 7
|
25 ± 8
|
24 ± 9
|
|
PAOP (mmHg)
|
6.6 ± 4.5
|
6.0 ± 4.9
|
5.3 ± 4.7
|
5.0 ± 4.0
|
|
MPAP-PAOP (mmHg)
|
16 ± 8
|
15 ± 6
|
19 ± 7*
|
19 ± 9
|
|
PVRI (dyne/s/cm5/m2)
|
671 ± 277
|
601 ± 247
|
471 ± 262*
|
492 ± 300*
|
|
MAP (mmHg)
|
87 ± 12
|
89 ± 11
|
91 ± 9
|
93 ± 12
|
|
SVRI (dyne/s/cm5/m2)
|
2524 ± 873
|
2625 ± 1012
|
1654 ± 541
|
1824 ± 683**
|
|
Qs/Qt (%)
|
23 ± 11
|
15 ± 6
|
28 ± 10*
|
17 ± 5
|
|
PaO2/FiO2 (mmHg)
|
322 ± 115
|
442 ± 103*
|
310 ± 93
|
419 ± 90*
|
|
PaCO2 (mmHg)
|
45 ± 11
|
44 ± 11
|
43 ± 11
|
45 ± 13
|
- *P < 0.05; **P < 0.01. CVP, cardiovenous pressure; INO, inhaled nitric oxide; MAP, mean systemic arterial pressure; MPAP, mean pulmonary arterial pressure; PAOP, pulmonary artery occluded pressure; PVRI, pulmonary vascular resistance index; SVI, systemic vascular index; SVRI, systemic vascular resistance index.
