Dysfunctional organ system | Criteria |
---|---|
Renal | Urine output ≤ 1 ml/kg per h or serum creatinine ≥ 100 μmol/l |
Respiratory | Ventilatory support with inspired oxygen fraction ≥ 0.4 for more than 5 days postoperatively |
Hepatic | Aspartate aminotransferase ≥ 500 IU/L or prothrombin time* ≤ 50% |
Cardiac | Need for catecholamines >24 h postoperatively† |
Haematological | Thrombocytes <100,000/μl |
Neurological | Seizures or coma |