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Table 3 Associations between the time to initiation of low-dose corticosteroid therapy and 28-day mortality after adjustments for potential confounding factors

From: Early initiation of low-dose corticosteroid therapy in the management of septic shock: a retrospective observational study

Time to initiation of low-dose corticosteroid therapy (hour)

Variables in the equation

 

Coefficient

SE

P -value

OR

95% CI

Crude state

0.0147

0.0074

0.0483

1.015

1.001-1.030

Adjusted statea

     

   Model 1

0.0147

0.0074

0.0483

1.015

1.001-1.030

   Model 2

0.0239

0.0088

0.0065

1.024

1.007-1.042

   Model 3

0.0249

0.0093

0.0075

1.025

1.007-1.044

  1. 95% CI, 95% confidence interval; OR, odds ratio; SE, standard error. aModel 1 was adjusted for age and gender. Model 2 was additionally adjusted for SAPS 3 and time to initiation of antibiotic therapy. Model 3 additionally included leukocytes, platelet, creatinine, prothrombin time, albumin, initial lactate, vasopressor dose, the need for mechanical ventilation and continuous renal replace therapy.
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