Table 2 Prediction of the occurrence of acute kidney injury in univariate and multivariate regression analysis Univariate analysis
Predictor | Hazard Ratio | P-value |
|---|---|---|
Age (yrs) | HR 1.03 (95%CI 0.99-1.06) | 0.06 |
Hx Heart Failure | HR 2.02 (95%CI 1.08-3.81) | 0.03 |
Hx Chronic Kidney Disease | HR 2.15 (95%CI 1.16-3.99) | 0.02 |
Steady State Creatinine > 110 μol/l | HR 2.21 (95%CI 1.16-4.23) | 0.02 |
Outpatient Diuretic Treatment | HR 2.36 (95%CI 1.03-5.41) | 0.04 |
Systolic Blood Pressure (mmHg) | HR 0.99 (95%CI 0.97-0.99) | 0.03 |
Loop Diuretic Dose during first 72h | HR 1.00 (95%CI 1.00-1.01) | < 0.01 |
Urea (mmo/l) | HR 1.09 (95%CI 1.04-1.15) | < 0.001 |
Uric Acid (mmol/l) | HR 1.00 (95%Ci 1.00-1.00) | 0.02 |
C-reactive protein (mg/l) | HR 1.01 (95%CI 1.00-1.01) | 0.03 |
Troponin T (ug/l) | HR 1.06 (95%CI 1.01-1.19) | 0.02 |
B-type natriuretic peptide (pg/ml) (for every increase of 100 pg/ml) | HR1.00 (95%CI 0.99-1.02) | 0.80 |
LV ejection fraction (%) | HR 0.99 (95%CI 0.97-1.02) | 0.53 |
Creatinine (mmol/l) (for every increase of 10 mml/l) | HR 1.13 (95%CI 1.01-1.20) | < 0.001 |
NGAL ng/ml (for every increase of 10 ng/ml) | HR 1.01 (95%CI 1.04-1.15) | < 0.001 |
NGAL > 94 ng/ml | HR 1.44 (96%CI 0.15-14.20) | 0.76 |
NGAL > 140 ng/ml | HR 3.40 (95%CI 1.61-7.15) | 0.001 |
Multivariate analysis | ||
Hx Heart Failure | HR 1.75 (95%CI 0.64-4.80) | 0.24 |
Steady State Creatinine > 110 μmol/l | HR 2.41 (95%CI 0.66-8.88) | 0.41 |
Systolic Blood Pressure (mmHg) | HR 1.01 (95%CI 0.99-1.02) | 0.43 |
Outpatient Diuretic Treatment | HR 1.25 (95%CI 0.32-4.02) | 0.58 |
Loop Diuretic Dose during first 72h | HR 1.00 (95%CI 0.99-1.00) | 0.86 |
C-reactive protein (mg/l) | HR 1.00 (95%CI 0.99-1.01) | 0.95 |
Troponin T (ug/l) | HR 3.72 (95%CI 0.02-13.53) | 0.63 |
Creatinine (mmol/l) (for every increase of 10 mml/l) | HR 1.12 (95%CI 1.00-1.24) | 0.04 |
NGAL (ng/ml) (for every increase of 10 ng/ml) | HR 1.05 (95%CI 0.98-1.13) | 0.18 |