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Table 1 Baseline Characteristics of 207 patients

From: Plasma neutrophil gelatinase-associated lipocalin for the prediction of acute kidney injury in acute heart failure

 

All patients

No AKI

AKI

P-values

Total number of patients

207

147 (71)

60 (29)

 

Age (year)

80 [74-85]

80 [73-84]

80 [76-86]

0.19

Female

85 (41)

59 (40)

26 (43)

0.53

Medical History

    

Arterial Hypertension

152 (73)

106 (72)

46 (76)

0.27

Heart Failure

103 (50)

67 (46)

36 (60)

0.03

Coronary artery disease

100 (48)

66 (45)

34 (57)

0.09

Diabetes mellitus

69 (33)

49 (33)

20 (33)

0.87

Chronic kidney disease

92 (44)

57 (39)

35 (58)

< 0.01

Neoplastic disease

27 (13)

20 (14)

7 (12)

0.27

Long term medication use

    

Diuretics

153 (74)

105 (71)

48 (80)

0.06

Betablockers

123 (59)

83 (54)

40 (66)

0.11

Nitrates

44 (21)

30 (20)

14 (23)

0.57

Renin Angiotensin System-Blockers

129 (62)

88 (61)

41 (68)

0.34

Aspirin

85 (41)

60 (41)

25 (42)

0.75

Anticoagulation

77 (37)

50 (34)

27 (45)

0.11

Vital status

    

Blood pressure (mmHg)

    

Systolic

136 [115-152]

138 [117-157]

130 [112-144]

0.05

Diastolic

84 [69-96]

84 [74-97]

75 [67-92]

0.09

Heart rate (per minute)

85 [73-102]

86 [74-100]

85 [75-107]

0.63

Respiratory rate (per minute)

20 [18-27]

20 [16-28]

22 [18-26]

0.63

Oxygen saturation (%)

97 [95-98]

96 [95-98]

97 [93-98]

0.91

Body Mass Index (kg/m2)

26 [23-30]

26 [23-30]

26 [24-30]

0.58

Noninvasive CVP (cmH20)

13 [9-18]

13 [8-20]

13 [8-17]

0.59

Laboratory values

    

LV ejection fraction (%)

40 [25-55]

45 [25-55]

40 [29-50]

0.87

Leucocytes (x109/L)

8.1 [6.5-10.6]

8.1[6.7-10.0]

8.2 [6.9-12.0]

0.23

Hemoglobin (g/l)

123 [114-139]

127 [120-139]

122 [107-139]

0.25

C-reactive protein (mg/l)

11.6 [4.2-32.3]

9.4 [4.1-32.9]

20.4 [8.1-40.3]

0.03

Urea (mmol/l)

9.2 [7.1-13.2]

8.9 [6.9-12.8]

11.8 [8.5-18.1]

< 0.01

Uric acid (mmol/l)

461 [370-582]

448 [347-576]

505 [407-624]

0.02

Creatinine (mmol/l)

100 [78-143]

97 [76-132]

140 [91-203]

< 0.01

Baseline eGFR (ml/min)*

52 [35-74]

57 [38-75]

42 [27-63]

< 0.01

NGAL (ng/ml)

79.6 [60.0-133.6]

75.4 [60.0-113.9]

114.5 [67.1-201.5]

< 0.01

BNP (pg/ml)

1377 [847-2428]

1321 [792-2491]

1470 [731-2444]

0.49

Troponin T (ug/l)

0.02 [0.01-0.04]

0.01 [0.01- 0.30]

0.03 [0.01-0.60]

< 0.01

  1. Data are presented as median [interquartile range], number of patients (%)as appropriate; Abbreviations:eGFR denotes estimated glomerular filtration rate, NGAL denotes Neutrophil gelatinase-associated lipocalin; BNP denotes B-type natriuretic peptide, CVP denotes central venous pressure