Extravascular lung water index improves the diagnostic accuracy of lung injury in patients with shock

Table 3 Sensitivity, specificity and positive and negative likelihood ratios of EVLW/ABW, EVLW/PBW and EVLW/PBV for diagnosis of acute lung injury, acute respiratory distress syndrome or severe lung injury

EVLW index	ALI	ARDS	sLI
EVLW/ABW
Sensitivity	0.50	0.53	0.44
Specificity	0.85	0.83	0.76
LR+	3.30	3.2	1.87
LR-	0.60	0.56	0.73
Pretest odds	0.55	0.42	0.21
Posttest odds +	1.80	1.33	0.40
Posttest odds -	0.32	0.23	0.16
EVLW/PBW
Sensitivity	0.61	0.60	0.67
Specificity	0.70	0.67	0.81
LR+	2.02	1.80	3.50
LR-	0.56	0.60	0.41
Pretest odds	0.56	0.42	0.21
Posttest odds +	1.10	0.75	0.75
Posttest odds -	0.30	0.25	0.09
EVLW/PBV
Sensitivity	0.89	0.87	1.0
Specificity	0.52	0.47	0.88
LR+	1.83	1.64	8.4
LR-	0.22	0.28	0
Pretest odds	0.55	0.42	0.21
Posttest odds +	1.00	0.68	1.79
Posttest odds -	0.12	0.12	0

ABW: actual body weight; ALI: acute lung injury; ARDS: acute respiratory distress syndrome; EVLW: extravascular lung water; LR-: negative likelihood ratio; LR+: positive likelihood ratio; PBV: pulmonary blood volume; PBW: predicted body weight; sLI: severe lung injury. Posttest odds given a positive (posttest odds +) or negative EVLW test (posttest odds -) are also shown. Positive EVLW tests were defined as EVLW/ABW > 10 ml/kg, EVLW/PBW > 10 ml/kg and EVLW/PBV > 1.5.

ISSN: 1364-8535