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Table 5 The base case economic evaluation results

From: A pragmatic multi-centre randomised controlled trial of fluid loading in high-risk surgical patients undergoing major elective surgery - the FOCCUS study

Base case ICER calculations

Threshold analysis*: probability of cost-effective at alternative values of willingness to pay for a QALY

(%)

 

Mean total cost (£)

Incremental cost (£)

Mean QALY

Incremental QALY

ICER (£/QALY)

£10,

000

£20,

000

£30,

000

£50,

000

Fluid loading

10,373

 

0.3527

  

84.4

86.5

89.4

92.0

Fluid control

11,739

-1,366

0.3175

0.0352

Dominated

15.6

13.5

10.6

8.0

Adjusted differences

(95% CI; P- value)*

 

-2,047

(-6,947 to 2,854; P = 0.413)

 

0.0431

(-0.0171 to 0.1033; P = 0.161)

     
  1. CI, confidence interval; ICER, incremental cost-effectiveness ratio; QALY, quality adjusted life year.
  2. * Adjusted for minimisation variables and baseline EQ-5D score and based on 1,000 bootstrap iterations.