From: Long-term psychological effects of a no-sedation protocol in critically ill patients
No Sedation (n= 13) | Sedation (n= 13) | p value | |
---|---|---|---|
Age (years) | 71 (58-74) | 63 (56-67) | 0.33 |
Female | 9 (69%) | 8 (62%) | 0.5 |
Weight (kg) | 80 (75-90) | 96 (70-103) | 0.26 |
Apache II | 20 (16-29) | 25 (21-26) | 0.20 |
SAPS II | 41 (34-49) | 46 (32-49) | 0.63 |
SOFA (at day 1) | 7 (5-9) | 7 (5-10.5) | 0.91 |
Ventilator-free days (28 days) | 23.15 (19.00-25.35) | 16.13 (3.92-22.67) | 0.12 |
Morphine (mg/kg/h)a | 0.0088 (0.0039-0.01676) | 0.0047 (0.0030-0.0060) | 0.24 |
Propofol (mg/kg/h)ab | 0 (0-1.2553) | 1.3996 (0.5178-2.0408) | 0.0127 |
Midazolam (mg/kg/h)a | 0 (0-0) | 0.0135 (0-0.0405) | 0.0029 |
Haloperidol (mg/kg/ha | 0.0039 (0-0.0202) | 0 (0-0) | 0.0125 |
Time from randomization to psychological interview (years) | 1.78 (1.46-2.10) | 2.04 (1.55-2.29) | 0.32 |
Time from hospital discharge to interview (years) | 1.72 (1.42-2.05) | 1.92 (1.47-2.20) | 0.49 |