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Table 2 Hemodynamic profile in response to endotoxemia

From: Dipyridamole augments the antiinflammatory response during human endotoxemia

  Placebo Dipyridamole Difference between groups
  Baseline 4 to 6 hours after LPS Baseline 4 to 6 hours after LPS ( P value)
HR (beats per minute) 65 ± 2 84 ± 2 67 ± 2 89 ± 1 0.59
SBP (mm Hg) 132 ± 1 121 ± 2 134 ± 2 114 ± 2 0.29
DBP (mm Hg) 76 ± 1 71 ± 2 74 ± 1 68 ± 1 0.6
MAP (mm Hg) 94 ± 1 87 ± 2 94 ± 1 83 ± 1 0.35
FBF ml/min/dl 2.7 ± 0.4 7.3 ± 0.8 4.3 ± 0.5 8.6 ± 1.2 0.87
  1. Data expressed as mean ± SEM. DBP, diastolic blood pressure; FBF, forearm blood flow; HR, heart rate; MAP, mean arterial pressure; SBP, systolic blood pressure. All LPS-induced changes were significant (P < 0.0001).