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Table 2 Hemodynamic profile in response to endotoxemia

From: Dipyridamole augments the antiinflammatory response during human endotoxemia

 

Placebo

Dipyridamole

Difference between groups

 

Baseline

4 to 6 hours after LPS

Baseline

4 to 6 hours after LPS

( P value)

HR (beats per minute)

65 ± 2

84 ± 2

67 ± 2

89 ± 1

0.59

SBP (mm Hg)

132 ± 1

121 ± 2

134 ± 2

114 ± 2

0.29

DBP (mm Hg)

76 ± 1

71 ± 2

74 ± 1

68 ± 1

0.6

MAP (mm Hg)

94 ± 1

87 ± 2

94 ± 1

83 ± 1

0.35

FBF ml/min/dl

2.7 ± 0.4

7.3 ± 0.8

4.3 ± 0.5

8.6 ± 1.2

0.87

  1. Data expressed as mean ± SEM. DBP, diastolic blood pressure; FBF, forearm blood flow; HR, heart rate; MAP, mean arterial pressure; SBP, systolic blood pressure. All LPS-induced changes were significant (P < 0.0001).
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Critical Care

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