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Table 5 The factors associated with in-hospital mortality

From: Detection of copeptin in peripheral blood of patients with aneurysmal subarachnoid hemorrhage

 

Non-survivals

(n = 32)

Survival

(n = 271)

P value

Sex (male/female)

12/20

119/152

0.489

Age (y)

45.4 ± 12.9

43.7 ± 12.3

0.469

WFNS score on admission

3.9 ± 0.7

2.2 ± 1.1

<0.001

Modified Fisher score on admission

4.3 ± 0.6

2.6 ± 0.8

<0.001

Aneurysmal location

  

0.599

   Posterior communication artery

5 (15.6%)

78 (28.8%)

 

   Internal carotid artery

6 (18.8%)

37(13.7%)

 

   Anterior communication artery

8 (25.0%)

58 (21.4%)

 

   Middle cerebral artery

4 (12.5%)

41 (15.1%)

 

   Anterior cerebral artery

4 (12.5%)

31 (11.4%)

 

   Posterior cerebral artery

3 (9.4%)

20 (7.4%)

 

   Vertebral artery

2 (6.3%)

6 (2.2%)

 

Surgery

17 (53.1%)

169 (62.4%)

0.310

Aneurysmal size (mm)

11.9 ± 5.1

6.7 ± 4.5

<0.001

Rebleeding

6 (18.8%)

10 (3.7%)

<0.001

Acute hydrocephalus

19 (59.4%)

71 (26.2%)

<0.001

Intracerebral hemorrhage

15 (46.9%)

24 (8.9%)

<0.001

Intraventricular hemorrhage

31 (96.9%)

41 (15.1%)

<0.001

External ventricular drain

30 (93.8%)

79 (29.2%)

<0.001

Angiographic vasospasm

30 (93.8%)

101 (37.3%)

<0.001

Computed tomography ischemia

16 (50.0%)

34 (12.6%)

<0.001

Admission time (hr)

5.4 ± 4.2

4.6 ± 3.6

0.276

Seizure

7 (21.9%)

37 (13.7%)

0.212

Plasma C-reactive protein level (mg/L)

9.0 ± 3.2

6.9 ± 2.6

<0.001

plasma D-dimer level (mg/L)

2.4 ± 1.1

2.0 ± 1.0

0.045

Plasma copeptin level (pmol/L)

31.8 ± 8.5

19.9 ± 8.2

<0.001

  1. Numerical variables were presented as mean ± standard deviation. Categorical variables were expressed as counts (percentage). Numerical variables were analyzed by Mann-Whitney U-test or unpaired Student t test. Categorical variables were analyzed by chi-square test or Fisher exact test. n indicates number of patients; WFNS, World Federation of Neurological Surgeons.