From: Detection of copeptin in peripheral blood of patients with aneurysmal subarachnoid hemorrhage
 | Non-survivals (n = 42) | Survival (n = 261) | P value |
---|---|---|---|
Sex (male/female) | 18/24 | 113/148 | 0.958 |
Age (y) | 45.4 ± 13.4 | 43.6 ± 12.2 | 0.389 |
WFNS score on admission | 4.0 ± 0.7 | 2.1 ± 1.0 | <0.001 |
Modified Fisher score on admission | 4.2 ± 0.6 | 2.5 ± 0.8 | <0.001 |
Aneurysmal location | Â | Â | 0.614 |
   Posterior communication artery | 8 (19.0%) | 75 (28.7%) |  |
   Internal carotid artery | 6 (14.3%) | 37(14.2%) |  |
   Anterior communication artery | 9 (21.4%) | 57 (21.8%) |  |
   Middle cerebral artery | 7 (16.7%) | 38 (14.6%) |  |
   Anterior cerebral artery | 6 (14.3%) | 29 (11.1%) |  |
   Posterior cerebral artery | 4 (9.5%) | 19 (7.3%) |  |
   Vertebral artery | 2 (4.8%) | 6 (2.3%) |  |
Surgery | 21 (50.0%) | 165 (63.2%) | 0.102 |
Aneurysmal size (mm) | 11.1 ± 5.3 | 6.6 ± 4.5 | <0.001 |
Rebleeding | 10 (23.8%) | 6 (2.3%) | <0.001 |
Acute hydrocephalus | 25 (59.5%) | 65 (24.9%) | 0.001 |
Intracerebral hemorrhage | 19 (45.2%) | 20 (7.7%) | <0.001 |
Intraventricular hemorrhage | 37 (88.1%) | 35 (13.4%) | <0.001 |
External ventricular drain | 38 (90.5%) | 71 (27.2%) | <0.001 |
Angiographic vasospasm | 38 (90.5%) | 93 (35.6%) | <0.001 |
Computed tomography ischemia | 18 (42.9%) | 32 (12.3%) | <0.001 |
Admission time (hr) | 5.5 ± 4.4 | 4.6 ± 3.5 | 0.128 |
Seizure | 9 (21.4%) | 35 (13.4%) | 0.171 |
Plasma C-reactive protein level (mg/L) | 8.7 ± 3.3 | 6.9 ± 2.6 | <0.001 |
plasma D-dimer level (mg/L) | 2.4 ± 1.0 | 2.0 ± 1.0 | 0.015 |
Plasma copeptin level (pmol/L) | 31.4 ± 8.3 | 19.5 ± 8.0 | <0.001 |