Risk factors for invasive fungal disease in critically ill adult patients: a systematic review

Table 5 Methodology and reporting assessment: general assessment

Study	Is study objective clearly described?	Are main outcomes measured clearly described?	Are patient characteristics clearly described?	Was study performed in multiple centres (more than two)?	Was analysis defined a priori?	Did analysis account for majority of known risk factors?	Was rationale behind inclusion of risk factors included?	Were risk factors clearly defined?
Agvald-Ohman et al., 2008 [28]	✓	✓	✓	x	x	x	x	x
Blumberg et al., 2001 [29]	✓	✓	✓	✓	✓	✓	x	x
Borzotta & Beardsley, 1999 [34]	✓	✓	✓	✓	✓	✓	x	✓
Chow et al., 2008 [30]	✓	✓	✓	✓	✓	✓	x	x
Ibàñez-Nolla et al., 2004 [31]	✓	✓	✓	x	✓	✓	x	x
Jordà-Marcos et al., 2007 [26]	✓	✓	✓	✓	✓	✓	x	✓
León et al., 2006 [27]	✓	✓	✓	✓	✓	✓	x	✓
Michalopoulos et al., 2003 [36]	✓	✓	✓	✓	✓	✓	✓	✓
McKinnon et al., 2001 [32]	✓	✓	✓	✓	✓	✓	✓	✓
Ostrosky-Zeichner et al., 2007 [37]	✓	✓	✓	✓	x	✓	x	x
Paphitou et al., 2005 [35]	✓	✓	✓	x	✓	✓	✓	x
Piarroux et al., 2004 [38]	✓	✓	✓	x	✓	n/a	n/a	n/a
Pittet et al., 1994 [33]	✓	✓	✓	x	x	✓	x	✓

n/a = not applicable (evaluation of clinical decision rule, no risk factor analysis).

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