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Table 2 Changes of gas exchanges, and respiratory rate during NIV according to treatment

From: Optimization of ventilator setting by flow and pressure waveforms analysis during noninvasive ventilation for acute exacerbations of COPD: a multicentric randomized controlled trial

 

Optimized Ventilation

Standard ventilation

P

After 30 minutes of NIV

   

   RR, cycles/minute

28 ± 6

26 ± 7

.197

   Vt/IBW, ml/Kg

7.8 ± 1.4

7.4 ± 1.8

.316

After 2 hours of NIV

   

   RR, cycles/minute

25 ± 4

24 ± 6

.285

   Vt/IBW, ml/Kg

8.0 ± 1.7

7.4 ± 1.8

.260

   PaO2/FiO2

220 ± 58

241 ± 49

.119

   HCO3-, mmol/l

33 ± 6

32 ± 7

.537

After 6 hours of NIV

   

   RR, cycles/minute

24 ± 4

24 ± 7

.827

   Vt/IBW, ml/Kg

8.0 ± 2.1

7.6 ± 2.1

.395

   PaO2/FiO2

235 ± 60

243 ± 37

.506

   HCO3-, mmol/l

33 ± 6

32 ± 7

.534

After 24 hours of NIV

   

   RR, cycles/minute

22 ± 6

22 ± 4

.932

   Vt/IBW, ml/Kg

8.1 ± 2.4

7.7 ± 2.1

.545

   PaO2/FiO2

235 ± 60

243 ± 37

.713

   HCO3-, mmol/l

35 ± 7

33 ± 6

.404

  1. Data reported as mean ± standard deviation. IBW, ideal body weight; RR, respiratory rate; Vt, tidal volume.
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