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Table 2 Changes of gas exchanges, and respiratory rate during NIV according to treatment

From: Optimization of ventilator setting by flow and pressure waveforms analysis during noninvasive ventilation for acute exacerbations of COPD: a multicentric randomized controlled trial

  Optimized Ventilation Standard ventilation P
After 30 minutes of NIV    
   RR, cycles/minute 28 ± 6 26 ± 7 .197
   Vt/IBW, ml/Kg 7.8 ± 1.4 7.4 ± 1.8 .316
After 2 hours of NIV    
   RR, cycles/minute 25 ± 4 24 ± 6 .285
   Vt/IBW, ml/Kg 8.0 ± 1.7 7.4 ± 1.8 .260
   PaO2/FiO2 220 ± 58 241 ± 49 .119
   HCO3-, mmol/l 33 ± 6 32 ± 7 .537
After 6 hours of NIV    
   RR, cycles/minute 24 ± 4 24 ± 7 .827
   Vt/IBW, ml/Kg 8.0 ± 2.1 7.6 ± 2.1 .395
   PaO2/FiO2 235 ± 60 243 ± 37 .506
   HCO3-, mmol/l 33 ± 6 32 ± 7 .534
After 24 hours of NIV    
   RR, cycles/minute 22 ± 6 22 ± 4 .932
   Vt/IBW, ml/Kg 8.1 ± 2.4 7.7 ± 2.1 .545
   PaO2/FiO2 235 ± 60 243 ± 37 .713
   HCO3-, mmol/l 35 ± 7 33 ± 6 .404
  1. Data reported as mean ± standard deviation. IBW, ideal body weight; RR, respiratory rate; Vt, tidal volume.