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Table 2 Overall clinical characteristics of patients with major trauma

From: Clinical relevance of single nucleotide polymorphisms within the entire NLRP3 gene in patients with major blunt trauma

Clinical characteristics

Patient data (N= 718)

Mean age ± SD (years)

40.6 ± 13.8

Age range (years)

18 to 65

Males/females, n

577/141

Mean ISS ± SD

22.5 ± 10.0

   ≥ 16 to < 25, n

413

   ≥ 25, n

305

Injured body regions, n

 

   Head

385

   Thorax

424

   Abdomen

249

   Extremities

431

Number of regions injured, n

 

   Two

306

   Three

177

   All four

37

Organ dysfunction, n (%)

299 (41.6%)

   One, n

215

   Two, n

57

   Three or above, n

27

Sepsis, n (%)

287 (40.0%)

Source of infection (%)

 

   Respiratory tract infection

42.5

   Primary bloodstream infection

20.2

   Urinary tract infection

18.3

   Catheter-associated infection

9.8

   Wound infection

7.1

   Others*

2.1

Pathogens (positive blood cultures) (%)

 

   Gram-negative

17.1

   Gram-positive

6.3

   Fungi

8.7

   Mixed Gram-negative and Gram-positive

11.1

Negative blood cultures

56.8

  1. *Other sites of infection included soft-tissue infection, bone infection and ear infection. ISS = Injury Severity Score.