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Table 1 Distribution of the six tag SNPs of the NLRP3 gene among trauma patients

From: Clinical relevance of single nucleotide polymorphisms within the entire NLRP3 gene in patients with major blunt trauma

  

MAF (%)

Genotypes, n(%)

 

SNPs

Number of patients

Patients

Database*

Wild type

Heterozygous

Variant

HWE test

rs2027432

718

5.5

8.9

642 (89.4)

73 (10.2)

3 (0.4)

0.73

rs3738448

705

19.2

16.7

454 (64.4)

231 (32.8)

20 (2.8)

0.18

rs12048215

718

26.0

25.6

398 (55.4)

267 (37.2)

53 (7.4)

0.42

rs4612666

711

46.1

40

193 (27.1)

380 (53.5)

138 (19.4)

0.06

rs1539019

718

40.7

43.3

251 (35.0)

349 (48.6)

118 (16.4)

0.93

rs10754558

714

40.8

50

246 (34.5)

354 (49.6)

114 (15.9)

0.54

  1. *Data are derived from the HapMap database for Chinese Han in Beijing (n = 45). HWE = Hardy-Weinberg equilibrium; MAF = minor allele frequency.