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Table 2 Baseline parameter ranges for study phases

From: Evaluation of a novel closed-loop fluid-administration system based on dynamic predictors of fluid responsiveness: an in silico simulation study

  Phase 1 Phase 2 Phase 3
  Min Max Min Max Min Max
Weight (kg) 60 100 70 85 70 85
Height (in) 62 72 65 68 65 68
HR (beats/min) 55 85 65 75 65 75
SBP (mm Hg) 105 145 110 130 110 130
DBP (mmHg) 60 90 70 80 70 80
LVEDV (ml) 130 150 130 150 130 150
LVESV (ml) 42 58 42 58 42 58
  1. DBP, diastolic blood pressure; LVEDV, left ventricular end-diastolic blood pressure; LVESV, left ventricular end-systolic volume; SBP, systolic blood pressure.