Skip to main content

Table 3 Blood pressure, laboratory values, end-organ damage and outcomes (in-hospital)

From: Characteristics, practice patterns, and outcomes in patients with acute hypertension: European registry for Studying the Treatment of Acute hyperTension (Euro-STAT)

Variables All patients
(n= 791)
Enrolment setting
   ED (n= 180) ICU (n= 382) Perioperative (n= 229)
Median blood pressure, mmHg (IQR)     
   Qualifying SBP 166 (141 to 190) 200 (174 to 220) 160 (138 to 180) 160 (140 to 180)
   Qualifying DBP 80 (68 to 95) 100 (90 to 110) 73 (64 to 85) 80 (68 to 90)
Median time from qualifying BP to initiation of IV antihypertensive therapy, minutes (IQR) 5.0 (2.0 to 17) 20 (5.0 to 30) 5.0 (1.0 to 15) 5.0 (1.0 to 5.0)
Median time from IV initiation to 10% decrease in SBP, minutes (IQR) 28 (11 to 60) 31 (18 to 87) 30 (12 to 70) 18 (8.0 to 43)
Median laboratory values (IQR)    
   Peak troponin 0.03 (0.01 to 0.23) 0.03 (0.01 to 0.12) 0.04 (0.01 to 0.33) 0.03 (0.01 to 0.23)
   Peak creatine kinase-MB 33 (9.4 to 88) 5.1 (3.8 to 78) 50 (31 to 152) 38 (24 to 79)
   Peak NT-proBNP 910 (295 to 2, 240) 1, 672 (429 to 2, 637) 1, 451 (428 to 2, 709) 359 (242 to 970)
   Peak BNP 99 (82 to 132) 116 (91 to 146) 20 (20 to 20) n/a
   Initial creatinine, μmol/L 89 (72 to 113) 94 (78 to 125) 91 (74 to 116) 83 (69 to 102)
   Peak creatinine, μmol/L 103 (82 to 146) 119 (99 to 222) 107 (84 to 151) 92 (73 to 122)
End-organ injurya, n (%)     
   Acute coronary syndrome (new) 25 (3.2) 22 (12) 2 (0.5) 1 (0.4)
Previous worsened 10 (1.3) 8 (4.4) 2 (0.5) 0 (0.0)
   Acute LV dysfunction/pulmonary oedema (new) 28 (3.5) 19 (11) 7 (1.8) 2 (0.9)
Previous worsened 20 (2.5) 16 (8.9) 4 (1.1) 0 (0.0)
   Aortic dissection (new) 5 (0.6) 2 (1.1) 3 (0.8) 0 (0.0)
Previous worsened 2 (0.3) 1 (0.6) 1 (0.3) 0 (0.0)
   Encephalopathy (new) 22 (2.8) 8 (4.4) 11 (2.9) 3 (1.3)
Previous worsened 2 (0.3) 1 (0.6) 0 (0.0) 1 (0.4)
   Acute kidney failure (new) 36 (4.6) 8 (4.4) 23 (6.0) 5 (2.2)
Previous worsened 19 (2.4) 5 (2.8) 12 (3.1) 2 (0.9)
   Stroke (new) 13 (1.6) 8 (4.4) 5 (1.3) 0 (0.0)
Previous worsened 7 (0.9) 3 (1.7) 2 (0.6) 2 (0.9)
Outcomes n (%)     
   ICU admission 114 (14) 17 (9.4) 19 (5.0)b 78 (34)
   Hypertension relapse 104 (13) 14 (7.8) 55 (14) 35 (15)
  1. BP = blood pressure; DBP = diastolic blood pressure; ED = emergency department; IV = intravenous; LV = left ventricular; n/a = not applicable; NT-proBNP = N-terminal prohormone of brain natriuretic peptide; SBP = systolic blood pressure. aCategories are not mutually exclusive. bReadmission to ICU.