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Table 1 Baseline patient characteristics and liver stiffness measurements

From: Increased liver stiffness denotes hepatic dysfunction and mortality risk in critically ill non-cirrhotic patients at a medical ICU

Parameter

All patients

Sepsis

Non-sepsis

Number

108

80

28

Sex (male/female)

64/44

50/30

14/14

Age median (range) (years)

68

(21 to 90)

68

(21 to 90)

61

(35 to 85)

APACHE-II score median (IQR)

22

(15 to 27)

23

(17 to 28)

19

(7 to 22)

SOFA score median (IQR)

11

(6 to 13)

11

(8 to 14)

9

(1 to 11)

ICU days median (IQR)

9.5

(4 to 26)

13.0

(5 to 28)

7.0

(3 to 16)

Death during ICU n (%)

23 (21%)

20 (25%)

3 (11%)

Death during follow-up n (%)

48 (44%)

41 (51%)

7 (25%)

Mechanical ventilation n (%)

83 (77%)

64 (80%)

19 (68%)

Ventilation time median (IQR) (h)

188

(1 to 1846)

229

(48 to 492)

99

(2 to 312)

pre-existing liver cirrhosis n (%)

8 (7%)

3 (4%)

5 (18%)

ascites (US*) moderate/massive n (%)

11 (10%)/

6 (6%)

4 (5%)/

3 (4%)

7 (25%)/

4 (5%)

pre-existing diabetes n (%)

32 (30%)

21 (26%)

11 (39%)

BMI median (range)

(m2/kg)

26.0

(22.7 to 29.1)

25.1

(22.5 to 28.2)

26.5

(24.3 to 32.5)

liver stiffness Day 1 median (IQR) (kPa)

9.7

(7.0 to 17.1)

11.0

(7.5 to 18.1)

9.4

(6.3 to 12.2)

liver stiffness Day 3 median (IQR) (kPa)

9.4

(7.3 to 17.7)

10.0

(7.4 to 18.2)

8.4

(6.8 to 27.2)

liver stiffness Day 7 median (IQR) (kPa)

10.1

(6.3 to 18.8)

8.7

(6.1 to 17.4)

11.9

(7.9 to 41.7)

  1. For quantitative variables, median and interquartile range (IQR) (in parenthesis) are given. Abbreviations are: APACHE, Acute Physiology and Chronic Health Evaluation; BMI, body mass index; ICU, intensive care unit; SOFA, sequential organ failure assessment; *ascites detected by abdominal ultrasound (US).