Table 1 Population description
Characteristics | TBI patients with refractory intracranial pressure (N= 50) | |
|---|---|---|
n (%) or median (IQR) | Mean ± SD | |
Age (years) | 40 (25-45) | 36 ± 13 |
Male n (%) | 46 (92) | |
ISS n (%) | 29 (25-34) | 29 ± 6 |
SAPS 2 | 45 (40-47) | 45 ± 9 |
Glasgow Coma Scale on scene | 6 (5-8) | 6 ± 2 |
Diagnosis n (%) | ||
Subarachnoid hemorrhage | 24 (48) | |
Cranial extradural hematoma | 19 (38) | |
Cerebral contusion | 40 (80) | |
Initial intracranial pressure (mm Hg) | 28 (25-34) | 31 ± 9 |
Initial values before starting HSS infusion | ||
Intracranial pressure (mm Hg) | 29 (26-34) | 31 ± 9 |
Cerebral perfusion pressure (mm Hg) | 61 (50-70) | 61 ± 13 |
Natremia (mmol/L) | 140 (138-143) | 140 ± 4 |
Plasma osmolarity (mmol/L) | 275 (268-281) | 279 ± 17 |
Norepinephrine before starting HSS infusion n (%) | 49 (98) | |
ICU length of stay (days) | 25 (9-36) | 27 ± 19 |
Glasgow Coma Scale at ICU discharge for survival patients | 14 (8-15) | 13 ± 7 |
Death in ICU n (%) | 13 (26) | / |
Glasgow Outcome Scale at 1 year | ||
1 n (%) | 17 | |
2 n (%) | 4 | |
3 n (%) | 4 | / |
4 n (%) | 12 | |
5 n (%) | 13 | |