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Figure 4 | Critical Care

Figure 4

From: Pharmacokinetics of prolonged infusion of high-dose dexmedetomidine in critically ill patients

Figure 4

Dexmedetomidine clearance at 116 steady states defined by a 15-hour constant-rate infusion in 12 subjects. Open triangles, open circles, and solid circles indicate an infusion rate of 0.1, 0.4 to 2.1, and 2.5 μg/kg/h, respectively. Each line represents one patient. In two patients, only one steady state was achieved, and the corresponding clearances are depicted with a single symbol.

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