From: Post cardiac surgery vasoplegia is associated with high preoperative copeptin plasma concentration
PCSV patients (n= 10) | Controls (n= 54) | P value | |
---|---|---|---|
Surgery | |||
Ascending aorta (%) | 2 (20) | 7 (13) | 0.63 |
Coronary artery bypass graft (%) | 0 (0) | 21 (39) | 0.02 |
Valve (%) | 8 (80) | 26 (48) | 0.09 |
Redo (%) | 3 (30) | 3 (6) | 0.04 |
Fluid administration | |||
Crystalloids (ml) | 20,000 (1,500 to 3,000) | 2,000 (2,000 to 25,000) | 0.97 |
Colloids (ml) | 0 (0 to 500) | 500 (0 to 500) | 0.73 |
Transfusion (packed red cell units) | 2 (0 to 5) | 0 (0 to 2) | 0.10 |
Perioperative treatments | |||
Number of patients treated with ephedrine (%) | 4 (40) | 23 (42.6) | 1.00 |
Dobutamine total dose (mg) | 35 (25 to 60) | 0 (0 to 0) | 0.001 |
Furosemid total dose (mg) | 5 (0 to 10) | 0 (0 to 0) | 0.161 |
AVP and copeptin | |||
AVP during CPB (pmol/l) | 9.3 (1.3 to 11.4) | 6.4 (1.8 to 18.4) | 0.78 |
Copeptin during CPB (pmol/l) | 50.8 (35.9 to 63.4) | 9.4 (3.77 to 36.3) | 0.02 |