Table 1 Preoperative characteristics
From: Post cardiac surgery vasoplegia is associated with high preoperative copeptin plasma concentration
PCSV patients (n= 10) | Controls (n= 54) | P value | |
|---|---|---|---|
Age (years) | 70 (57 to 77) | 67 (60 to 76) | 0.71 |
Male (%) | 7 (70) | 36 (67) | 1.00 |
Body mass index | 25.7 (23.1 to 28.6) | 26.3 (24.3 to 28.0) | 0.62 |
Preoperative status | |||
LVEF (%) | 50 (30 to 60) | 60 (50 to 70) | 0.03 |
Urea (mmol/l) | 7.3 (6.4 to 15.2) | 7.3 (5.9 to 10.8) | 0.38 |
Na+ (mmol/l) | 137 (134 to 139) | 140 (138 to 141) | 0.01 |
Osmolarity (mOsmol/l) | 292 (284 to 296) | 294 (290 to 298) | 0.06 |
Hemoglobin (g/dl) | 12.3 (10.1 to 15.0) | 13.2 (11.7 to 14.6) | 0.32 |
Platelets (109/l) | 196.5 (131 to 241) | 219.5 (181 to 252) | 0.10 |
Comorbidities | |||
Hypertension (%) | 5 (50) | 24 (44) | 0.75 |
Diabetes (%) | 4 (40) | 7 (13) | 0.06 |
Euroscore | 9.5 (6 to 14) | 6 (5 to 8) | 0.02 |
Preoperative treatments | |||
Beta-blocker (%) | 4 (40) | 28 (52) | 0.73 |
ACE inhibitor or sartan (%) | 5 (50) | 37 (69) | 0.29 |
Calcium antagonist (%) | 1 (10) | 11 (20) | 0.67 |
Diuretic (%) | 9 (90) | 26 (48) | 0.02 |
Statin (%) | 6 (60) | 32 (59) | 1.00 |
AVP and copeptin | |||
AVP (pmol/ml) | 4.3 (1.4 to 6.3) | 2.1 (0.9 to 5.1) | 0.34 |
Copeptin (pmol/l) | 30.1 (9.8 to 69) | 4.8 (3.0 to 9.2) | < 0.001 |