Table 1 Clinical and biological data at admission according to the guideline for diagnosis of sepsis
From: Diagnostic value of urine sTREM-1 for sepsis and relevant acute kidney injuries: a prospective study
Characteristics | SIRS | Sepsis | ||
|---|---|---|---|---|
N = 16 | total n = 88 | sepsis n = 35 | severe sepsis n = 53 | |
Age (years) | 51 ± 18 | 60 ± 19 | 58 ± 21 | 62 ± 17 |
Gender (n, %) | ||||
Male | 3 (19) | 23 (26) | 24 (69) | 41 (77) |
Female | 13 (81) | 65 (74) | 11 (31) | 12 (24) |
WBC counts (×10∧9/L) | 11.3 ± 2.8 | 12.9 ± 6.7 | 10.5 ± 3.9 | 14.4 ± 7.7# |
Serum CRP (mg/dl) | 11.4 (5.9, 15.2) | 9.5 (4.1, 17.2) | 8.1 (2.5, 14.7) | 11.8 (6.1, 18.6) |
Serum PCT (ng/ml) | 1.2 (0.3, 9.5) | 2.7 (0.4, 11.1) | 0.4 (0.1 to 2.1) | 4.5 (1.2 to 19.4)# |
Urine sTREM-1 (pg/ml) | 11.8 (3.6, 24.1) | 61.5 (21.3, 173.7)* | 28.0 (10.5, 78.8) | 83.3 (39.6, 259.7)# |
Renal characteristics | ||||
Urinary output (ml/Kg/hr) | - | 1.2 ± 0.6 | 1.3 ± 0.5 | 1.1 ± 0.7 |
SCr (μmmol/L) | 83.2 (69.25, 104.75) | 85 (60.5, 134.4) | 65.9 (48.0, 99.9) | 90.8 (64.4, 167.7)# |
BUN (mmol/L) | 7.9 (4.9, 13.2) | 10.4 (7.5, 16.9) | 8.0 (6.5, 10.6) | 12.7 (8.8 (28.9))# |
APACHE II score | 11.5 ± 7.6 | 17.5 ± 7.5* | 13.4 ± 6.1 | 20.2 ± 7.1# |
SOFA score | - | 8.6 ± 3.7 | 5.8 ± 2.9 | 10.0 ± 3.5# |
MV (n, %) | 12 (75.0) | 74 (86.0) | 29 (82.9) | 45 (84.9) |
CRRT (n, %) | 2 (12.5) | 25 (28.4) | 5 (14.3) | 20 (37.7)# |
AKI (n, %) | 2 (12.5) | 36 (39.8)* | 4 (11.4) | 31 (58.5)# |
Etiological factors (n, %) | ||||
Pulmonary infection | - | 75 (85.2) | 31 (88.6) | 44 (83.0) |
Abdominal infection | - | 22 (25.0) | 7 (20.0) | 15 (28.3) |
Urinary tract infection | - | 25 (28.4) | 13 (37.1) | 12 (22.6) |
Trauma/postoperative infection | - | 33 (37.5) | 10 (28.6) | 23 (43.4) |
Bacteremia | - | 19 (21.6) | 9 (25.7) | 10 (18.9) |
Catheter-related infections | - | 13 (14.8) | 8 (22.9) | 5 (9.4) |
Others | - | 4 (4.5) | 0 (0.0) | 4 (7.5) |
Underlying diseases (n, %) | ||||
Hypertension | 5 (31.2) | 32(332 (36.4) | 12 (34.3) | 20 (37.7) |
Diabetes | 1 (6.2) | 14 (15.9) | 5 (14.3) | 5 (9.4) |
COPD | 1 (6.2) | 9 (10.2) | 5 (14.3) | 4 (7.5) |
Coronary heart disease | 4 (25.0) | 17 (19.3) | 5 (14.3) | 12 (22.6) |
Immunosuppressed | 0 (0.0) | 9(10.2) | 2 (5.7) | 7 (13.2) |
Nervous system disease | 2 (12.5) | 12(13.6) | 5 (14.3) | 7 (13.2) |
CKD | 1 (6.2) | 5(5.7) | 1 (2.9) | 4 (7.5) |
Mortality rate (n, %) | 1 (6.2) | 41(46.6)* | 7 (20.0) | 34 (64.2)# |