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Table 1 Demographics and clinical characteristics of the patients based upon ICU mortality

From: Early natural killer cell counts in blood predict mortality in severe sepsis

Demographic and clinical characteristics Survivors
(n= 29)
Nonsurvivors
(n= 21)
Total population
(n= 50)
Survivors vs nonsurvivors
P value
Age (years) 66.0 (20.0) 72.0 (14) 68.5 (19.2) 0.048
Males 18 (62%) 14 (66.6%) 32 (64%) n.s.
APACHE II score at ICU admission 18.0 (15.0) 23.0 (10.0) 20.5 (13.2) n.s.
SOFA score at ICU admission 7.0 (6.0) 9.0 (2.0) 8.0 (4.0) n.s.
Comorbidities     
   Cardiovascular disease 8 (26.6%) 7 (35%) 15 (30%) n.s.
   COPD 2 (6.6%) 6 (30%) 8 (16%) 0.025
   Chronic renal failure or dialysis 2 (6.6%) 2 (10%) 4 (8%) n.s.
   Diabetes mellitus types 1 and 2 10 (33.3%) 7 (35%) 17 (34%) n.s.
   Alcohol abuse 2 (6.6%) 1 (5%) 3 (6%) n.s.
   Hypertension 12 (41.3%) 7 (33.3%) 19 (38%) n.s.
   Neoplasia 3 (10%) 5 (25%) 8 (16%) n.s.
   Obesity 2 (6.6%) 1 (5%) 3 (6%) n.s.
Diagnostic at ICU admission     
   Severe sepsis 11 (36.6%) 1 (5%) 12 (24%) 0.007
   Septic shock 18 (62%) 20 (95.2%) 38 (76%) 0.007
Presumed source of infection     
   Lower respiratory tract/pneumonia 14 (46.6%) 9 (45%) 23 (46%) n.s.
   Urogenital 6 (20%) 3 (15%) 9 (18%) n.s.
   Intra-abdominal 2 (6.6%) 3 (15%) 5 (10%) n.s.
   Catheter- or device-related 1 (3.3%) 1 (5%) 2 (4%) n.s.
   Skin (soft tissues) 2 (6.6%) 1 (5%) 3 (6%) n.s.
   Prosthesis 2 (6.6%) 0 (0%) 2 (4%) n.s.
   Central nervous system 1 (3.3%) 0 (0%) 1 (2%) n.s.
   Other/unknown 2 (6.8%) 4 (19%) 6 (12%) n.s.
Documented microbial agent     
   Gram-positive 8 (26%) 6 (30%) 14 (28%) n.s.
   Gram-negative 10 (34.4%) 9 (42.8%) 19 (38%) n.s.
   Fungi 2 (6.6%) 1(5%) 3 (6%) n.s.
  1. Continuous variables are expressed as medians (IQR). All other data are raw numbers (%). Proportions were compared using the Χ2 test or Fisher's exact test where appropriate. APACHE II: Acute Physiology and Chronic Health Evaluation II; COPD: chronic obstructive pulmonary disease; SOFA: sequential organ failure assessment score; n.s. = not significant.