Table 1 Demographics and clinical characteristics of the patients based upon ICU mortality
From: Early natural killer cell counts in blood predict mortality in severe sepsis
Demographic and clinical characteristics | Survivors (n= 29) | Nonsurvivors (n= 21) | Total population (n= 50) | Survivors vs nonsurvivors P value |
|---|---|---|---|---|
Age (years) | 66.0 (20.0) | 72.0 (14) | 68.5 (19.2) | 0.048 |
Males | 18 (62%) | 14 (66.6%) | 32 (64%) | n.s. |
APACHE II score at ICU admission | 18.0 (15.0) | 23.0 (10.0) | 20.5 (13.2) | n.s. |
SOFA score at ICU admission | 7.0 (6.0) | 9.0 (2.0) | 8.0 (4.0) | n.s. |
Comorbidities | ||||
Cardiovascular disease | 8 (26.6%) | 7 (35%) | 15 (30%) | n.s. |
COPD | 2 (6.6%) | 6 (30%) | 8 (16%) | 0.025 |
Chronic renal failure or dialysis | 2 (6.6%) | 2 (10%) | 4 (8%) | n.s. |
Diabetes mellitus types 1 and 2 | 10 (33.3%) | 7 (35%) | 17 (34%) | n.s. |
Alcohol abuse | 2 (6.6%) | 1 (5%) | 3 (6%) | n.s. |
Hypertension | 12 (41.3%) | 7 (33.3%) | 19 (38%) | n.s. |
Neoplasia | 3 (10%) | 5 (25%) | 8 (16%) | n.s. |
Obesity | 2 (6.6%) | 1 (5%) | 3 (6%) | n.s. |
Diagnostic at ICU admission | ||||
Severe sepsis | 11 (36.6%) | 1 (5%) | 12 (24%) | 0.007 |
Septic shock | 18 (62%) | 20 (95.2%) | 38 (76%) | 0.007 |
Presumed source of infection | ||||
Lower respiratory tract/pneumonia | 14 (46.6%) | 9 (45%) | 23 (46%) | n.s. |
Urogenital | 6 (20%) | 3 (15%) | 9 (18%) | n.s. |
Intra-abdominal | 2 (6.6%) | 3 (15%) | 5 (10%) | n.s. |
Catheter- or device-related | 1 (3.3%) | 1 (5%) | 2 (4%) | n.s. |
Skin (soft tissues) | 2 (6.6%) | 1 (5%) | 3 (6%) | n.s. |
Prosthesis | 2 (6.6%) | 0 (0%) | 2 (4%) | n.s. |
Central nervous system | 1 (3.3%) | 0 (0%) | 1 (2%) | n.s. |
Other/unknown | 2 (6.8%) | 4 (19%) | 6 (12%) | n.s. |
Documented microbial agent | ||||
Gram-positive | 8 (26%) | 6 (30%) | 14 (28%) | n.s. |
Gram-negative | 10 (34.4%) | 9 (42.8%) | 19 (38%) | n.s. |
Fungi | 2 (6.6%) | 1(5%) | 3 (6%) | n.s. |