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Table 4 Change in adjusted Area under the Receiver Operating Characteristic Curve

From: Dynamic lactate indices as predictors of outcome in critically ill patients

NAME

Hospital AUCADJ

P-value*

ICU AUCADJ

P-value*

(1) Established risk factors

0.820 ± 0.01

 

0.873 ± 0.01

 

(1) + LACADM

0.822 ± 0.01

0.16

0.875 ± 0.01

0.24

(1) + LACΔ24%

0.824 ± 0.01

0.006

0.879 ± 0.01

0.009

(1) + LACΔ24

0.825 ± 0.01

0.005

0.879 ± 0.01

0.03

(1) + LACMAX24

0.827 ± 0.01

0.007

0.883 ± 0.01

0.015

(1) + LACTW24

0.831 ± 0.01

0.0001

0.887 ± 0.01

0.0005

(1) + LACMIN24

0.832 ± 0.01

< 0.0001

0.886 ± 0.01

< 0.0001

(1) + LACTW & LACΔ24

0.838 ± 0.01**

< 0.0001

0.895 ± 0.01**

< 0.0001

  1. *compared to model (1) with established risk factors (APACHE II, diagnosis, age, gender, ventilation, surgery, date of admission and hospital)
  2. **P < 0.01 compared to all individual measure of lactate
  3. APACHE II, Acute Physiology and Chronic Health Evaluation II; Apache II, diagnosis, age, gender, ventilation, surgery, date of admission, mortality adjusting for established predictors of mortality; AUCADJ, adjusted Area under the Receiver Operating Characteristic Curve; HVHF, high-volume hemofiltration; LACADM, admission lactate; LACTW24, time weighted lactate; LACMAX24, maximum lactate; LACMIN24, minimum lactate; LACΔ24, delta lactate; LAC%Δ24, percentage change in lactate in the first 24 hours