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Table 3 Multivariate models for the prediction of hospital and ICU mortality

From: Dynamic lactate indices as predictors of outcome in critically ill patients

Effect

Hospital mortality

P-value

ICU mortality

p-value

 

Odds ratio (95% CI)

 

Odds ratio (95% CI)

 

APACHE II score

1.13 (1.11 to 1.14)

< 0.0001

1.13 (1.11 to 1.15)

< 0.0001

Age (yr)

1.02 (1.02 to 1.03)

< 0.0001

1.01 (1.00 to 1.02)

0.004

LACTW24 (mmom.L-1)

1.37 (1.29 to 1.45)

< 0.0001

1.43 (1.35 to 1.52)

< 0.0001

LACΔ24 (mmom.L-1)

1.15 (1.10 to 1.20)

< 0.0001

1.18 (1.13 to 1.24)

< 0.0001

Diagnosis*

 

< 0.0001

 

< 0.0001

Mechanical ventilation

1.93 (1.52 to 2.45)

< 0.0001

2.81 (1.95 to 4.05)

< 0.0001

Hospital*

 

0.0001

 

0.006

Admission date (decreased risk per year)

0.91 (0.83 to 0.99)

0.04

0.88 (0.78 to 1.00)

0.05

Surgical patients

0.67 (0.53 to 0.84)

0.0007

0.80 (0.59 to 1.08)

0.15

Number of measurements

0.98 (0.95 to 1.01)

0.23

1.01 (0.97 to 1.04)

0.76

Female v male

0.96 (0.81 to 1.14)

0.66

0.99 (0.79 to 1.23)

0.90

  1. *categorical variable, odds ratios excluded
  2. APACHE II, Acute Physiology and Chronic Health Evaluation; LACTW24, time weighted lactate; LACΔ24, delta lactate-change in lactate in the first 24 hours