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Table 1 Baseline characteristics of the 105 patients

From: Presence of tobramycin in blood and urine during selective decontamination of the digestive tract in critically ill patients, a prospective cohort study

 

Mean ± SD

Nr (%) or

Median (IQR)

Age (ys)*

65.24 ± 14.57

66 (55.5 to 75.0)

Male sex

 

70 (66.7)

Body weight (kgs)*

81.1 ± 17.3

80 (70 to 90)

BMI

27.2 ± 5.6

26.3 (23.5 to 29.3)

Admission type

  

   • Medical

 

79 (75.2)

   • Cardiosurgical

 

10 (9.5)

   • Other surgical

 

16 (15.2)

Sepsis

 

34 (32.4)

CRP admission (mg/L)

89.1 ± 116

26.0 (3.0 to 160.6)

APACHE II score

27.4 ± 9.0

26.5 (20.0 to 34.0)

APACHE II PM

0.57 ± 0.28

0.59 (0.31 to 0.84)

APACHE III score

102 ± 35

97.5 (73.0 to 125.8)

APACHE IV PM

0.55 ± 0.31

0.56 (0.26 to 0.85)

SOFA admission

9 ± 4

9 (7 to 11)

Mechanical ventilation

 

104 (99.0)

MAP admission (mmHg)

80.6 ± 21.9

79 (62.0 to 94.0)

Dopamine admission (μg/kg/minute)

11.1 ± 13.7

5.9 (2.4 to 14.3)

Noradrenalin admission (μg/kg/minute)

0.05 ± 0.13

0.00 (0.00 to 0.04)

Lowest pH a

7.2 ± 0.18

7.2 (7.08 to 7.30)

Lowest bicarbonate a

17.8 ± 6.2

17.3 (13.8 to 22.3)

Lowest PO2 (mmHg) a

74.0 ± 23.0

70 (60.3 to 82.0)

PF ratio (mmHg/fraction)

244 ± 144

206 (151 to 294)

Creatinine before admissionb

80 ± 31

77 (56 to 98)

Creatinine (μmol/L)

118 ± 86.6

98.5 (71.0 to 133.3)

Urea (mmol/L)

11 ± 7

8 (6 to 14)

Urinary output d1(ml)

2,711 ± 1,851

2,378 (1,174 to 3,969)

Urinary output d1(ml/kg/h)

1.5 ± 1.1

1.2 (0.6 to 2.1)

RIFLE 1,2,3 c

  

0

60 (58.3)

 

1

15 (14.6)

 

2

16 (15.5)

 

3

12 (11.7)

 

Chronic dialysis

 

2 (2%)

Bilirubin (μmol/L)

14 ± 17

9 (5 to 16)

Hemoglobin (mmol/L)

6.8 ± 1.6

6.8 (5.8 to 8.2)

Platelets (giga)

236 ± 144

209 (151 to 298)

  1. * Normally distributed variables.
  2. APACHE, Acute Physiology and Chronic Health Evaluation; IQR, interquartile range; PM, predicted mortality; SAPS, Simplified Acute Physiology Score; SD, standard deviation; SOFA, Sequential organ failure score.
  3. a within two hours of ICU admission, b creatinine of the chronic dialysis patients not included, c RIFLE acronym for risk of acute kidney injury: Risk = 1, Injury = 2, Failure = 3. The chronic dialysis patients were excluded from the RIFLE classification.