| FFP outcomes: plasma fibrinogen levels | Fibrinogen concentrate outcomes: plasma fibrinogen levels | ||||
---|---|---|---|---|---|---|
Type of study | Increased/higher | No difference | Decreased/lower | Increased/higher | No difference | Decreased/lower |
RCT | 2 (vs preadministration) [38, 43] 1 (vs comparator) [41] | 1 (vs preadministration) [108] | - | - | ||
Non RCT or prospective comparator | 1 (vs comparator) [23] | 1 (vs preadministration/comparator) [109] | 1 (vs comparator) [44] | 1 (vs comparator) [55] | - | - |
Retrospective comparator | 1 (vs comparator) [30] | - | - | 1 (vs comparator) [26] | - | - |
Controlled and/or comparator study outcomes, n (percentage of outcomes within intervention group) | 5 (46%) | 4 (36%) | 2 (18%) | 4 (100%) | 0 | 0 |
Prospective noncomparator | 1 (vs preadministration) [53] | - | - | - | - | - |
Retrospective noncomparator | 1 (vs preadministration) [70] | - | 1 (vs preadministration) [110] | - | - | |
Case report | - | - | - | - | ||
Study outcomes, n (percentage of outcomes within intervention group) | 7 (44%) | 4 (25%) | 5 (31%) | 17 (100%) | 0 | 0 |