Table 8 Evidence for the effect of each intervention on ICU and/or hospital length of stay
| FFP outcomes: ICU and/or hospital length of stay |
Fibrinogen concentrate outcomes: ICU and/or hospital length of stay | |||||
|---|---|---|---|---|---|---|
| Type of study | Reduced | No difference | Increased | Reduced | No difference | Increased |
| RCT | - | 1 (ICU) [50] | - |
1 (ICU) [56] 1 (hospital) [56] | - | - |
| Non RCT or prospective comparator | 1 (hospital) [24] |
2 (ICU) [24, 87] 1 (hospital) [87] |
1 (ICU) [77] 1 (hospital) [77] | 1 (ICU) [55] | 1 (hospital) [55] | - |
| Retrospective comparator | 1 (ICU) [32, 33] |
2 (ICU) [3, 79] 5 (hospital) [3, 39, 40, 66, 79] |
7 (ICU) [39, 66, 67, 69, 81, 83, 105]* 3 (hospital) [67, 69, 81] | 1 (ICU) [26] | 1 (hospital) [26] | - |
| Controlled and/or comparator study outcomes, n (percentage of all outcomes within intervention group) | 2 (8%) | 11 (44%) | 12 (48%) | 4 (67%) | 2 (33%) | 0 |
| Prospective noncomparator | - | - | - | - | - | - |
| Retrospective noncomparator | - |
1 (ICU) [107] 1 (hospital) [107] | 2 (ICU) [98, 106] | - | - | - |
| Case report | - | - | - | - | - | - |
| Study outcomes, n (percentage of outcomes within intervention group) | 2 (7%) | 13 (45%) | 14 (48%) | 4 (67%) | 2 (33%) | 0 |