| FFP outcomes: allogeneic transfusions | Fibrinogen concentrate outcomes: allogeneic transfusions | ||||
---|---|---|---|---|---|---|
Type of study | Reduction | No difference | Increase | Reduction | No difference | Increase |
RCT | - | 1 (postoperative) [54] | - | |||
Non RCT or prospective comparator | - | 1 (intraoperative) [23] 1 (postoperative) [23] | 1 (postoperative) [44] | 1 (postoperative) [55] | - | - |
Retrospective comparator | 1 (postoperative) [39] 1 > 24 hours postoperative) [30] | 1 (postoperative) [47] | - | 1 (intraoperative) [26] 1 (postoperative) [26] | - | - |
Controlled and/or comparator study outcomes, n (percentage of all outcomes within intervention group) | 5 (23%) | 14 (63%) | 3 (14%) | 5 (63%) | 3 (37%) | 0 |
Prospective noncomparator | - | 1 (postoperative) [53] | - | - | - | - |
Retrospective noncomparator | 1 (postoperative) [70] | - | - | 3 (postoperative) [59, 72, 74] 1 (perioperative) [73] | - | - |
Case report | - | - | - | - | - | |
Study outcomes (percentage of outcomes, n (within intervention group) | 6 (25%) | 15 (63%) | 3 (12%) | 16 (84%) | 3 (16%) | 0 |