| FFP outcomes: blood loss | Fibrinogen concentrate outcomes: blood loss | ||||
---|---|---|---|---|---|---|
Study type | Reduction | No difference | Increase | Reduction | No difference | Increase |
RCT | - | - | 1 (postoperative) [54] | 1 (postoperative) [56] | - | |
Non RCT or prospective comparator | - | 1 (postoperative) [44] | 1 (postoperative) [55] | - | - | |
Retrospective comparator | 1 (perioperative) [34] | 1 (perioperative) [42] | - | 1 (postoperative) [26] | - | - |
Controlled and/or comparator study outcomes, n (percentage of all outcomes within intervention group) | 1 (5%) | 18 (90%) | 1 (5%) | 3 (75%) | 1 (25%) | 0 |
Prospective noncomparator | - | 1 (postoperative) [53] | - | - | - | - |
Retrospective noncomparator | - | 1 (postoperative) [52] | - | 1 (perioperative) [59] | - | - |
Case report | - | 1 (perioperative) [51] | - | - | - | |
Study outcomes, n (percentage of outcomes within intervention group) | 1 (4%) | 21 (92%) | 1 (4%) | 10 (91%) | 1 (9%) | 0 |