Characteristics | Sodium bicarbonate administration within first 24 hours of ICU stay (n= 57) | No sodium bicarbonate administration within the first 24 hours of ICU stay (n= 98) | P value |
---|---|---|---|
Age (years) | 62 ± 16 | 64 ± 17 | 0.26 |
Admitting diagnosis group | |||
Septic shock | 23 (40) | 31 (32) | 0.30 |
Hemorrhagic shock | 8 (14) | 8 (8) | 0.28 |
Cardiogenic shock | 2 (4) | 9 (9) | 0.33 |
Cardiac arrest | 5 (9) | 14 (14) | 0.45 |
Others | 19 (33) | 36 (37) | 0.73 |
SAPS II upon ICU admission | 71 ± 23 | 64 ± 22 | 0.10 |
SOFA upon ICU admission | 11 ± 4 | 10 ± 4 | 0.15 |
Vasopressor administration upon ICU admission | 49 (86) | 81 (83) | 0.65 |
Mechanical ventilation upon ICU admission | 30 (52) | 54 (55) | 0.86 |
Renal replacement therapy within first 24 hours of ICU stay | 15 (26) | 16 (17) | 0.20 |
Plasma pH upon ICU admission | 7.07 ± 0.15 | 7.10 ± 0.09 | 0.39 |
Bicarbonatemia upon ICU admission (mmol/L) | 12.6 ± 5.2 | 15.4 ± 5.6 | < 0.01 |
PaCO2 upon ICU admission (mmHg) | 41.6 ± 12.6 | 52.1 ± 22.8 | < 0.01 |
Base excess upon ICU admission (mmol/L) | -15.6 ± 6.3 | -12.5 ± 5.7 | < 0.01 |
Anion gap corrected upon ICU admission (mmol/L) | 31 ± 11 | 26 ± 8 | 0.02 |
Lactatemia upon ICU admission (mmol/L) | 9.3 ± 6.9 | 7.8 ± 5.5 | 0.32 |
Length of vasopressor treatment (days) | 3.9 ± 4.7 | 5.3 ± 8.8 | 0.35 |
Length of mechanical ventilation (days) | 6.6 ± 10.7 | 8.3 ± 14.0 | 0.85 |
ICU length of stay (days) | 10.1 ± 15.5 | 11.4 ± 15.7 | 0.32 |
Mortality in the ICU | 34 (60) | 55 (56) | 0.73 |