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Table 3 Bundle compliance by implementation phases: baseline, education, and quality improvement phases 1 to 4

From: Outcome effectiveness of the severe sepsis resuscitation bundle with addition of lactate clearance as a bundle item: a multi-national evaluation

 

All patients (n= 556)

Baseline (n= 128)

Education (n= 104)

QI1 (n= 104)

QI2 (n= 85)

QI3 (n= 80)

QI4 (n= 55)

P value

Lactate measured

488 (87.8)

99 (77.3)

78 (76.5)

100 (96.2)

84 (98.8)

77 (96.3)

50 (90.9)

<0.01

Blood cultures before antibiotics

514 (92.4)

101 (78.9)

97 (93.3)

99 (95.2)

82 (96.5)

80 (100.0)

55 (100.0)

<0.01

Antibiotics administered by 3 hours

555 (99.8)

128 (100.0)

103 (99.0)

104 (100.0)

85 (100.0)

80 (100.0)

55 (100.0)

0.50

Fluid bolus given

506 (91.0)

98 (76.6)

102 (98.1)

100 (96.2)

75 (88.2)

78 (97.5)

53 (96.4)

<0.01

Achieve CVP >8 mmHg by 6 hours

319 (57.4)

55 (43.0)

58 (55.8)

59 (56.7)

57 (67.1)

52 (65.0)

38 (69.1)

<0.01

Achieve MAP >65 mmHg by 6 hours

530 (95.3)

117 (92.1)

103 (100.0)

100 (96.2)

80 (94.1)

78 (97.5)

52 (94.5)

0.08

Achieve ScvO2 >70% by 6 hours

250 (45.0)

23 (18.0)

33 (31.7)

58 (55.8)

51 (60.0)

50 (62.5)

35 (63.6)

<0.01

Lactate clearance

331 (59.5)

68 (53.1)

43 (41.3)

63 (60.6)

60 (70.6)

61 (76.3)

36 (65.5)

<0.01

Primary SSC Bundle completion

192 (34.5)

17 (13.3)

28 (26.9)

39 (37.5)

39 (45.9)

39 (48.8)

30 (54.5)

<0.01

Modified SSC Bundle completion

162 (29.1)

13 (10.2)

24 (23.1)

33 (31.7)

34 (40.0)

34 (42.5)

24 (43.6)

<0.01

  1. Results reported as count (column %). CVP, central venous pressure; MAP, mean arterial pressure; QI, quality improvement; ScvO2, central venous oxygen saturation; SSC, Surviving Sepsis Campaign.