Skip to main content

Table 3 Acute hospital mortality and odds ratios for acute hospital mortality for all patients and for each subgroup before and after Genetic Matching

From: Is Drotrecogin alfa (activated) for adults with severe sepsis, cost-effective in routine clinical practice?

 

DrotAA

n/N

(percentage)

Control

n/N

(percentage)

Odds ratio (95% CI) for acute hospital mortality for DrotAA versus control

Overall: two to five organ systems failing

   

   Unmatched

490/1,076 (45.54)

817/1,650 (49.52)

0.85 (0.72, 0.98)

   GenMatch

508/1,076 (47.25)

875/1,650 (53.04)

0.79 (0.71, 0.87)

Two organ systems failing

   

   Unmatched

80/198 (40.40)

221/630 (35.08)

1.26 (0.81, 1.67)

   GenMatch

93/198 (46.98)

228/630 (36.23)

1.56 (1.25, 1.85)

Three to five organ systems failing

   

   Unmatched

410/878 (46.70)

596/1,020 (58.43)

0.62 (0.51, 0.74)

   GenMatch

423/878 (48.16)

616/1,020 (60.38)

0.61 (0.53, 0.69)

  1. CI, confidence interval; DrotAA, Drotrecogin alfa (activated); GenMatch, Genetic Matching.