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Table 1 Clinical characteristics in survivors and nonsurvivors

From: Serial increase of IL-12 response and human leukocyte antigen-DR expression in severe sepsis survivors

Patient characteristics

Survivors (n= 23)

Nonsurvivors (n= 12)

Mean age, years (± SEM)

73.0 ± 3.2

73.2 ± 3.3

Males, n (%)

15 (65)

9 (75)

Mean APACHE II score (± SEM)

27.1 ± 1.6

32.7 ± 2.1

History, n (%)

  

   Chronic obstructive pulmonary disease

8 (35)

1 (8)

   Heart failure

3 (13)

0 (0)

   Pneumoconiosis

2 (9)

1 (8)

   Bronchiectasis

2 (9)

0 (0)

   Hypertension

8 (35)

2 (17)

   Diabetes mellitus

4 (17)

3 (25)

   Previous cerebral vascular accident

5 (22)

2 (17)

   End-stage renal disease

1 (4)

1 (8)

   Liver cirrhosis

1 (4)

3 (25)

   Active malignancy

3 (13)

5 (42)

Infection source, n (%)

  

   Pneumonia

19 (83)

10 (84)

   Urinary tract infection

4 (17)

0 (0)

   Catheter infection

0 (0)

1 (8)

   Biliary tract infection

0 (0)

1 (8)

Initial antibiotics for pathogens, n (%)

  

   Sensitive

12 (52)

6 (50)

   Resistant

6 (26)

6 (50)

   No pathogen isolated

5 (22)

0 (0)

Adverse events, n (%)

  

   New arrhythmia

1 (4)

2 (17)

   Gastrointestinal bleeding

3 (13)

2 (17)

   Acute renal failure

11 (48)

8 (67)

   Shock

15 (65)

12 (100)*

   Thrombocytopenia

5 (22)

7 (58)*

   Jaundice

0 (0)

2 (17)

   Bacteremia

1 (4)

4 (33)*

  1. SEM = standard error of the mean; APACHE II = Acute Physiology and Chronic Health Evaluation II. *P < 0.05 compared with survivors by the Mann-Whitney U test, χ2 test or Fisher's exact test.