Patient characteristics | Survivors (n= 23) | Nonsurvivors (n= 12) |
---|---|---|
Mean age, years (± SEM) | 73.0 ± 3.2 | 73.2 ± 3.3 |
Males, n (%) | 15 (65) | 9 (75) |
Mean APACHE II score (± SEM) | 27.1 ± 1.6 | 32.7 ± 2.1 |
History, n (%) | ||
Chronic obstructive pulmonary disease | 8 (35) | 1 (8) |
Heart failure | 3 (13) | 0 (0) |
Pneumoconiosis | 2 (9) | 1 (8) |
Bronchiectasis | 2 (9) | 0 (0) |
Hypertension | 8 (35) | 2 (17) |
Diabetes mellitus | 4 (17) | 3 (25) |
Previous cerebral vascular accident | 5 (22) | 2 (17) |
End-stage renal disease | 1 (4) | 1 (8) |
Liver cirrhosis | 1 (4) | 3 (25) |
Active malignancy | 3 (13) | 5 (42) |
Infection source, n (%) | ||
Pneumonia | 19 (83) | 10 (84) |
Urinary tract infection | 4 (17) | 0 (0) |
Catheter infection | 0 (0) | 1 (8) |
Biliary tract infection | 0 (0) | 1 (8) |
Initial antibiotics for pathogens, n (%) | ||
Sensitive | 12 (52) | 6 (50) |
Resistant | 6 (26) | 6 (50) |
No pathogen isolated | 5 (22) | 0 (0) |
Adverse events, n (%) | ||
New arrhythmia | 1 (4) | 2 (17) |
Gastrointestinal bleeding | 3 (13) | 2 (17) |
Acute renal failure | 11 (48) | 8 (67) |
Shock | 15 (65) | 12 (100)* |
Thrombocytopenia | 5 (22) | 7 (58)* |
Jaundice | 0 (0) | 2 (17) |
Bacteremia | 1 (4) | 4 (33)* |