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Table 5 Results of multivariate logistic regression modeling for the outcomes of Sequential Organ Failure Assessment score ≥ 2 at 24 hours and in-hospital mortality in all groupsa

From: The association of near-infrared spectroscopy-derived tissue oxygenation measurements with sepsis syndromes, organ dysfunction and mortality in emergency department patients with sepsis

Parameter included Parameter retained (Yes/No (P value))b
  Outcomes
  SOFA ≥ 2 at 24 hoursc In-hospital mortality
Age, years No (0.086) No (0.089)
Serum lactate Yes (< 0.001) Yes (< 0.001)
Systolic blood pressure Yes (0.014) No (0.571)
StO2   
   Initial Yes (0.046) No (0.128)
   Occlusion No (0.199) No (0.669)
   Recovery Yes (0.037) Yes (0.003)
   Multivariate model AUC (95% CI) 0.79 (0.72 to 0.87) 0.88 (0.80 to 0.95)
   Log (p/(1 - p)) 5.6651 + 0.5135*Lactate - 0.0173*SBP - 0.0529*Initial - 0.2465*Recovery -1.7582 + 0.5084*Lactate - 0.5271*Recovery
Odds ratios (95% CI)   
   Serum lactate (1 mEq/L increase) 1.7 (1.2 to 2.2) 1.7 (1.3 to 2.2)
   SBP (10 mmHg decrease) 1.2 (1.0 to 1.4) NA
   Initial (10% decrease) 1.7 (1.0 to 2.9) NA
   Upslope (1%/second decrease) 1.3 (1.0 to 1.6) 1.7 (1.2 to 2.4)
  1. aSOFA: Sequential Organ Failure Assessment; StO2: tissue oxygen saturation; AUC: area under the curve; 95% CI: 95% confidence interval; SBP: systolic blood pressure; NA: not applicable. bStepwise backward elimination technique used. The P value in parentheses after "Yes" is the P value in the resultant model. The P value after "No" is the P value when the eliminated parameter was included back into the final model for reevaluation after elimination. cFor patients in the control group in which the SOFA score at 24 hours was not measured, a SOFA score < 2 was assumed. For patients with a history of chronic renal insufficiency or end-stage renal disease, the total SOFA score used did not include the renal portion of the score.