The association of near-infrared spectroscopy-derived tissue oxygenation measurements with sepsis syndromes, organ dysfunction and mortality in emergency department patients with sepsis

Table 3 Serum lactate, systolic blood pressure and InSpectra parameters stratified by in-hospital survival in all groups^a

Parameter	Died (n= 25)	Survived (n= 143)	P value*	AUC (95% CI)
Serum lactate, mmol/L	4.7 ± 2.7 (4.2) (n = 24)	1.9 ± 1.4 (1.5) (n = 128)	< 0.001	0.85 (0.76 to 0.93)
Systolic blood pressure, mmHg	105 ± 30 (102)	122 ± 30 (123)	0.004	0.68 (0.56 to 0.80)
Mean age, years	69 ± 14 (72)	62 ± 18 (67)	0.100	0.60 (0.49 to 0.72)
StO₂
Initial (%)	76 ± 11 (79)	79 ± 7 (80)	0.341	0.56 (0.43 to 0.69)
Occlusion (%/minute)	-8.8 ± 5.1 (-8.2)	-12.0 ± 4.7 (-11.9)	0.002	0.70 (0.57 to 0.83)
Recovery (%/second)	1.7 ± 1.5 (1.3)	3.7 ± 1.7 (3.8)	< 0.001	0.81 (0.71 to 0.91)

^aAUC: area under the curve; 95% CI: 95% confidence interval; StO₂: tissue oxygen saturation; *Wilcoxon two-sample test or Fisher's exact test, as appropriate. Data are means ± SD (medians).

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