From: Red blood cell transfusion and outcomes in patients with acute lung injury, sepsis and shock
Characteristics | Transfused (n= 53) | Not transfused (n= 232) | P value |
---|---|---|---|
Age, years | 53 (17) | 52 (16) | 0.52 |
Males | 30 (57) | 123 (53) | 0.22 |
Race | Â | Â | Â |
   White | 35 (66) | 149 (64) | 0.03 |
   Black | 15 (28) | 40 (17) |  |
   Other | 3 (6) | 43 (19) |  |
Chronic comorbidities | Â | Â | Â |
   Diabetes | 11 (21) | 40 (18) | 0.59 |
   Hepatic failure | 2 (4) | 1 (0.4) | 0.03 |
   Alcohol use | 2 (4) | 26 (12) | 0.13 |
   Prior myocardial infarction | 0 (0) | 11 (5) | 0.12 |
   Congestive heart failure | 0 (0) | 8 (4) | 0.18 |
Admission type | Â | Â | Â |
   Medical ICU | 47 (89) | 211 (91) | 0.87 |
   Surgical ICU | 5 (9) | 18 (8) |  |
   Other | 1 (2) | 3 (1) |  |
Randomization | Â | Â | Â |
   Liberal fluid (vs. conservative) | 25 (47) | 114 (49) | 0.80 |
   Pulmonary artery (vs. central venous) catheter | 28 (53) | 125 (54) | 0.89 |
   APACHE III score | 118 (27) | 103 (2) | < 0.01 |
   Days from ALI diagnosis to randomization | 0 (0, 1) | 0 (0, 1) | 0.99 |
   Days from hospital admission to randomization | 2 (1, 7) | 2 (1, 4) | 0.18 |
   Days from ICU admission to randomization | 1 (1, 2) | 1 (1, 2) | 0.89 |
   PaO2/FiO2 ratio at randomization | 107 (63 to 150) | 108 (73 to 154) | 0.47 |
Physiological parameters during exposure window | Â | Â | Â |
   Hemoglobin nadir, g/dL | 8.5 (1.4) | 9.7 (1.4) | < 0.01 |
   cVO2/mVO2 ratio nadir | 67 (12) | 67 (13) | 0.76 |
   MAP nadir, mmHg | 62 (8) | 63 (9) | 0.47 |
   Mean MAP, mmHg | 71 (8) | 73 (9) | 0.19 |
   Total fluid received, L | 6.8 (4.4) | 5.5 (3.2) | 0.01 |
   Multiple pressors | 27 (51) | 120 (52) | 0.92 |