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Table 3 Univariate and multivariate logistic regression analysis used to differentiate survivors and non-survivors

From: Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis

  

Univariate (n= 66)

Multivariate (n= 66)

  

OR

95% CI

P value

OR

95% CI

P value

Gender

Male

1.00

-

-

   
 

Female

5.22

1.25-21.82

0.023

8.19a

0.75-89.05

0.084

     

4.56b

0.65-31.81

0.126

     

5.47c

1.15-25.99

0.033

Age, years

≤62

1.00

-

-

   
 

> 62

2.51

0.59-10.69

0.214

   

APACHE II

score

≤18

1.00

-

-

   
 

> 18

2.53

0.63-9.89

0.192

   

SOFA score

≤7

1.00

-

-

   
 

> 7

2.02

0.48-8.63

0.341

   

ΔmHLA-DR3

> 4.8

1.00

-

-

 

-

 
 

≤4.8

75.00

8.04-699.44

< 0.001

94.71a

7.64-1174.27

< 0.001

ΔmHLA-DR7

> 9

1.00

-

-

   
 

≤9

54.00

5.99-486.08

< 0.001

51.04b

5.35-486.94

< 0.001

ΔmHLA-DR7-3

> 3.5

1.00

     
 

≤3.5

7.20

1.39-37.23

0.019

7.46c

1.34-41.39

0.022

  1. aΔmHLA-DR3, bΔmHLA-DR7, and cΔmHLA-DR7-3 were entered into multivariate logistic regression model separately with adjustment of gender. ΔmHLA-DR3 and ΔmHLA-DR7 were defined as the value change in mHLA-DR on days 3 and 7 compared with that on day 0, and ΔmHLA-DR7-3 was defined as the value change in mHLA-DR on day 7 compared with that on day 3. APACHE II, Acute Physiology and Chronic Health Evaluation II; CI, confidence interval; OR, odds ratio; SOFA, Sequential Organ Failure Assessment.
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