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Table 1 Linear mixed model on the mean (95% confidence interval) changes in mHLA-DR at every measure point in the survivor and non-survivor groups

From: Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis

 

Day 0

Day 3

Day 7

   
 

Number

mHLA-DR

Number

mHLA-DR

Number

mHLA-DR

ΔmHLA-DR3

ΔmHLA-DR7

ΔmHLA-DR7-3

Survivor

56

62.97

(56.38~69.55)

56

69.42

(62.92~75.92)

56

79.87

(73.96~85.78)

6.45a

(2.50~10.40)

16.90b

(11.85~21.95)

10.45c

(6.19~14.71)

Non-survivor

23

56.77

(46.49~67.05)

16

55.08

(44.26~65.90)

10

61.32

(49.79~72.84)

-1.69d

(-8.95~5.57)

4.55e

(-5.96~15.06)

6.24f

(-3.28~15.76)

Between-

groups difference

      

8.14g

(-0.12~16.40)

12.35h

(0.70~24.00)

4.21i

(-6.21~14.64)

  1. ΔmHLA-DR3 and ΔmHLA-DR7 were defined as the value change in mHLA-DR on days 3 and 7 compared with that on day 0, and ΔmHLA-DR7-3 was defined as the value change in mHLA-DR on day 7 compared with that on day 3. In the comparison of mean mHLA-DR differences in the same group between every measurement point, P values were a0.002, b < 0.001, c < 0.001, d0.644, e0.392, and f0.195. In the comparison of ΔmHLA-DR differences between two groups within the same measurement point, P values were g0.053, h0.038, and i0.423. CI, confidence interval; mHLA-DR, monocyte human leukocyte antigen-DR.