Parameters | TP (n= 20) | AVP (n= 20) | Control (n= 20) | P value |
---|---|---|---|---|
CI (L/min/m2) | Â | Â | Â | Â |
   Baseline | 3.8 (3.1 to 5.4) | 4.0 (3.2 to 4.9) | 4.0 (3.5 to 4.6) | 0.96 |
   6 hours | 4.0 (3.1 to 5.1) | 3.5 (3.0 to 4.0)* | 4.0 (3.4 to 4.9) | 0.28 |
HR (bpm) | Â | Â | Â | Â |
   Baseline | 104 (86 to 113) | 99 (83 to 119) | 104 (86 to 111) | 1.00 |
   6 hours | 88 (82 to 100) | 91 (75 to 117) | 91 (85 to 114) | 0.64 |
MAP (mmHg) | Â | Â | Â | Â |
   Baseline | 71 (68 to 75) | 72 (69 to 75) | 71 (68 to 75) | 0.97 |
   6 hours | 74 (72 to 75) | 72 (68 to 75) | 74 (68 to 75) | 0.31 |
MPAP (mmHg) | Â | Â | Â | Â |
   Baseline | 30 (27 to 35) | 31 (28 to 36) | 29 (27 to 32) | 0.42 |
   6 hours | 29 (24 to 33) | 29 (26 to 34) | 31 (26 to 33) | 0.65 |
PAOP (mmHg) | Â | Â | Â | Â |
   Baseline | 16 (14 to 19) | 18 (16 to 20) | 18 (15 to 20) | 0.26 |
   6 hours | 17 (13 to 20) | 18 (15 to 22) | 18 (14 to 20) | 0.45 |
RAP (mmHg) | Â | Â | Â | Â |
   Baseline | 13 (10 to 15) | 15 (12 to 17) | 13 (10 to 14) | 0.13 |
   6 hours | 13 (10 to 15) | 14 (11 to 16) | 11 (10 to 14) | 0.22 |
LVSWI (g/m/m-2) | Â | Â | Â | Â |
   Baseline | 29 (24 to 41) | 26 (24 to 35) | 30 (22 to 37) | 0.85 |
   6 hours | 32 (26 to 44) | 24 (23 to 39) | 30 (21 to 44) | 0.11 |
DO2I (mL·min-1/m2) |  |  |  |  |
   Baseline | 437 (391 to 604) | 460 (396 to 677) | 470 (399 to 550) | 0.92 |
   6 hours | 461 (364 to 587) | 416 (369 to 473) | 509 (431 to 600) | 0.13 |
O2-ER (%) | Â | Â | Â | Â |
   Baseline | 25 (23 to 30) | 26 (22 to 30) | 31 (27 to 36) | 0.05 |
   6 hours | 32 (25 to 35) | 29 (24 to 38) | 35 (29 to 41) | 0.15 |
SvO2 (%) | Â | Â | Â | Â |
   Baseline | 75 (68 to 77) | 73 (67 to 80) | 69 (66 to 76) | 0.30 |
   6 hours | 70 (66 to 77) | 70 (59 to 77) | 67 (59 to 72) | 0.26 |
Hba (g/dL) | Â | Â | Â | Â |
   Baseline | 8.3 (8.0 to 9.5) | 8.9 (8.3 to 9.8) | 8.7 (8.0 to 9.3) | 0.50 |
   6 hours | 8.3 (8.0 to 8.8)* | 8.6 (8.1 to 9.7) | 9.0 (8.6 to 10.0) | 0.005 |
pHa (-log10c(H+)) | Â | Â | Â | Â |
   Baseline | 7.30 (7.24 to 7.34) | 7.31 (7.27 to 7.37) | 7.31 (7.28 to 7.36) | 0.62 |
   6 hours | 7.39 (7.31 to 7.43) | 7.33 (7.28 to 7.40) | 7.31 (7.25 to 7.37) | 0.08 |
BE (mmol/L) | Â | Â | Â | Â |
   Baseline | -3.9 (-7.0 to -1.2) | -3.1 (-8.0 to 1.8) | -2.9 (-5.9 to 1.6) | 0.65 |
   6 hours | -2.2 (-4.7 to 2.4) | -3.4 (-5.7 to 1.5) | -4.0 (-6.2 to 0.5) | 0.41 |
Lactate (mmol/L) | Â | Â | Â | Â |
   Baseline | 1.8 (1.2 to 2.9) | 2.3 (1.4 to 3.6) | 2.5 (1.9 to 3.0) | 0.67 |
   6 hours | 2.1 (1.5 to 2.8) | 2.3 (1.4 to 3.6) | 2.6 (2.1 to 3.7) | 0.45 |
Fluid input (mL/6 hours) | Â | Â | Â | Â |
   Baseline | n/a | n/a | n/a | n/a |
   6 hours | 875 (790 to 950) | 910 (830 to 975) | 895 (800 to 990) | 0.51 |