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Table 6 Univariate and multivariate logistic regression analysis of predictors of mortality

From: Community-acquired polymicrobial pneumonia in the intensive care unit: aetiology and prognosis

Variable

Univariate analysis

 

Multivariate analysisa

 
 

Odds ratio

95% CI

P value

Adjusted odds ratio

95% CI

P value

Age ≥ 65 years

2.49

1.17 to 5.32

0.018

3.06

1.27 to 7.41

0.013

Diabetes mellitus

2.25

1.06 to 4.76

0.034

-

-

-

Neurological disease

2.04

0.95 to 4.38

0.068

2.63

1.07 to 6.48

0.036

Chronic liver disease

5.63

2.20 to 14.39

< 0.001

8.99

2.91 to 27.77

< 0.001

Fever

0.49

0.24 to 1.01

0.053

-

-

-

Pneumonia severity index IV to V

4.77

1.43 to 15.91

0.011

-

-

-

Multilobar infiltration

2.28

1.13 to 4.60

0.021

-

-

-

Number of pathogens identifiedb

  

0.055

-

-

-

   None

1

-

-

   

   Monomicrobial

1.56

0.72 to 3.38

0.26

-

-

-

   Polymicrobial

3.31

1.25 to 8.77

0.016

-

-

-

Inappropriate empiric treatment

11.23

4.44 to 28.38

< 0.001

10.79

3.97 to 29.30

< 0.001

  1. aHosmer-Lemeshow goodness-of-fit test, P = 0.81. bThe P value corresponds to differences between the three groups (none, one or more than one pathogen). The odds ratio and 95% confidence interval (CI) of monomicrobial and polymicrobial pneumonia are related to cases with no pathogen identified.