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Table 3 Distribution of the causative microorganisms identified in 196 patients with community-acquired pneumonia

From: Community-acquired polymicrobial pneumonia in the intensive care unit: aetiology and prognosis

Microorganism

Monomicrobial aetiology (n= 157)

Polymicrobial aetiology (n= 39)

P value

Two pathogens (n= 33)

Three pathogens (n= 6)

Streptococcus pneumoniae

94 (60)

28 (72)

0.17

23 (70)

5 (83)

Streptococcus pyogenes

1 (1)

1 (3)

0.36

1 (3)

-

Streptococcus viridans a

-

1 (3)

0.20

1 (3)

-

Staphylococcus aureus (MSSA)

4 (3)

3 (8)

0.12

2 (6)

1 (17)

Staphylococcus aureus (MRSA)

5 (3)

9 (23)

< 0.001

5 (15)

4 (67)

Haemophilus influenzae

4 (3)

4 (10)

0.029

3 (9)

1 (17)

Moraxella catarrhalis

1 (1)

2 (5)

0.041

1 (3)

1 (17)

Gram-negative enteric bacillib

6 (4)

7 (18)

0.002

5 (15)

2 (33)

Pseudomonas aeruginosa

6 (4)

8 (21)

< 0.001

6 (18)

2 (33)

Respiratory viruses

16 (10)

15 (39)

< 0.001

14 (42)

1 (17)

   Rhinovirus

2 (1)

2 (5)

0.13

2 (6)

-

   Adenovirus

1 (1)

1 (3)

0.36

1 (3)

-

   Respiratory syncitial virus

2 (1)

2 (5)

0.13

2 (6)

-

   Influenza virus A

10 (6)

9 (23)

0.002

8 (24)

1 (17)

   Influenza virus B

1 (1)

1 (3)

0.36

1 (3)

-

   Legionella pneumophila

10 (6)

1 (3)

0.36

1 (3)

-

Atypical

10 (6)

5 (13)

0.18

4 (12)

1 (17)

   Mycoplasma pneumoniae

4 (3)

2 (5)

0.40

2 (6)

-

   Chlamydophila pneumoniae

4 (3)

2 (5)

0.40

1 (3)

1 (17)

   Coxiella burnetii

2 (1)

1 (3)

0.49

1 (3)

-

  1. Data presented as n (%). Percentages refer to the total number of patients of each group (monomicrobial vs. polymicrobial). The most frequent combinations in cases with two pathogens were S. pneumoniae with respiratory viruses (11 cases), P. aeruginosa (three cases), and H. influenzae, Gram-negative enteric bacilli and atypicals in two cases each. The most frequent combination in cases with three pathogens was S. pneumoniae, Gram-negative enteric bacilli and methicillin-resistant Staphylococcus aureus (MRSA) in two cases. P value refers to a statistical comparison of cases with monomicrobial aetiology and polymicrobial aetiology. MSSA, methicillin-susceptible Staphylococcus aureus. aS. viridans isolated from a pleural fluid specimen. bIncluding Escherichia coli, Klebsiella pneumoniae, Serratia marcescens.